Acarbose is a Medicine belongs to Oral Hypoglycemic Drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 467   Edition : 38,

  ►   Brandname : Acarbay,Asucrose,Glucobay,Precose,beixi

  ►  Strength : Tablet with 25  Mg, Tablet with 50  Mg, Tablet with 100  Mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 766   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Basic & Clinical pharmacology    Page : 766   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Type 2 diabetes mellitus Oral 25 50 mg Tablet Given daily.

Ref :-  Book : Martindale    Page : 471   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Type 2 diabetes mellitus Oral 150 300 mg

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1992   Edition : 19,
Precaution :- If a Patient is using 'Acarbose' drug in acute kidney injury disease, then Please contraindicated   if he ever suffered from Diabetic Nephropathy disease.
►  Side Effect : gastrointestinal disturbance, Flatulence, diarrhea, Pain, transient and reversible increase in liver enzyme values, Abdominal distension, , central obesity,
Ref :-   Book : Martindale    Page : 471   Edition : 37,    Page :    Edition : , Martindale    Page : 121212   Edition : 121212,

►  Drug Interaction : Drug interaction of Acarbose is with , , , ,  Insulin , Neomycin , Digoxin ,
Ref :-   Book : Martindale    Page : 467   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Acarbose may enhance the effects of other antidiabetics, including insulin, and a reduction in their dosage may be needed. Use with gastrointestinal adsorbents and digestive enzyme preparations can diminish the effects of acarbose and should be avoided. Neomycin and colestyramine may enhance the effects of acarbose and a reduction in its dosage may be required. Acarbose may inhibit the absorption of digoxin. ,
Ref :-   Book : Martindale    Page : 467   Edition : 38,


►  Contraindication : hepatic impairment, inflammatory bowel disease, chronic intestinal diseases, Gastrointestinal obstruction, in conditions which may deteriorate as a result of increased gas formation, such as hernia,
Ref :-   Book : Martindale    Page : 467   Edition : 38,
  ►  Mechanism of Action :   Acarbose is an inhibitor of alpha glucosidases, especially sucrase. This slows the digestion and absorption of carbohydrates in the small intestine and hence reduces the increase in blood-glucose concentrations after a carbohydrate load.,
Ref :-   Book : Martindale    Page : 466   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Berries with same pathway, Rosemarinic acid with same pathway, Resveratrol with same pathway, catechol with same pathway, Protocatechuic Acid with same pathway, Quercetin with same pathway,

  ►  Pathway with its reference as follows :-
  • Alpha glucosidase inhibitor --- (Kwon, Y., Apostolidis, E., Labbe, R. and Shetty, K. (2007). Inhibition of Staphylococcus aureus by Phenolic Phytochemicals of Selected Clonal Herbs Species of Lamiaceae Family and Likely Mode of Action through Proline Oxidation. Food Biotechnology, 21(1), pp.71-89. )
  • Alpha glucosidase inhibitor --- (Kwon, Y., Apostolidis, E., Labbe, R. and Shetty, K. (2007). Inhibition of Staphylococcus aureus by Phenolic Phytochemicals of Selected Clonal Herbs Species of Lamiaceae Family and Likely Mode of Action through Proline Oxidation. Food Biotechnology, 21(1), pp.71-89. )
  • Alpha glucosidase inhibitor --- ( Kwon, Y., Apostolidis, E., Labbe, R. and Shetty, K. (2007). Inhibition of Staphylococcus aureus by Phenolic Phytochemicals of Selected Clonal Herbs Species of Lamiaceae Family and Likely Mode of Action through Proline Oxidation. Food Biotechnology, 21(1), pp.71-89. )
  • Alpha glucosidase inhibitor --- ( Kwon, Y., Apostolidis, E., Labbe, R. and Shetty, K. (2007). Inhibition of Staphylococcus aureus by Phenolic Phytochemicals of Selected Clonal Herbs Species of Lamiaceae Family and Likely Mode of Action through Proline Oxidation. Food Biotechnology, 21(1), pp.71-89. )
  • Alpha glucosidase inhibitor --- (Kwon, Y., Apostolidis, E., Labbe, R. and Shetty, K. (2007). Inhibition of Staphylococcus aureus by Phenolic Phytochemicals of Selected Clonal Herbs Species of Lamiaceae Family and Likely Mode of Action through Proline Oxidation. Food Biotechnology, 21(1), pp.71-89. )
  • Alpha glucosidase inhibitor --- ( Kwon, Y., Apostolidis, E., Labbe, R. and Shetty, K. (2007). Inhibition of Staphylococcus aureus by Phenolic Phytochemicals of Selected Clonal Herbs Species of Lamiaceae Family and Likely Mode of Action through Proline Oxidation. Food Biotechnology, 21(1), pp.71-89. )

  •   ►  URL -- http://www.tandfonline.com/doi/abs/10.1080/08905430701191205,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- VITAMIN B12 with Decrease in Nutrient Level,

      ►  Reference :-
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart.

  •   ►  URL -- http://197.14.51.10:81/pmb/AGROALIMENTAIRE/Handbook%20of%20Nutrition.pdf,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- EPHEDRA with It ele`vate blood sugar level .,

      ►  Reference :-
  • PDR for Herbal medicines. (2000) (4th ed.). U.S.

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf,

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 471   Edition : 37,


    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA