Adenosine is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1325   Edition : 37,

  ►   Brandname : Adenoject,Adenocor,Adenocard,Adenoscan,Ai Duo

  ►  Strength : Injection with 3  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 250   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 1324   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Proxysmal supraventricular tachycardia IV 3 mg
2 Diagnosis of supraventricular tachycardias IV 3 mg Injection
3 Myocardial imaging IV infusion 140 micrograms/kg/min Injection Given up to 6 minutes.

Ref :-  Book : Martindale    Page : 1324   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Proxysmal supraventricular tachycardia 1 Year 12 Year IV 100 microgram/kg Injection

Ref :- Book : Martindale    Page : 1324   Edition : 37,
►  Side Effect : nausea, lightheadedness, flushing, headache, chest pain, apprehension, dyspepsia, bronchospasm, Arrhythmias, bradycardia, heart block, hypotension, reflex tachycardia, abdominal discomfort, throat discomfort, neck discomfort, jaw discomfort, worsen arrhythmias, ,
Ref :-   Book : Martindale    Page : 1324   Edition : 37,    Page :    Edition : ,

►  Drug Interaction : Drug interaction of Adenosine is with ,  Dipyridamole , Theophylline ,
Ref :-   Book : Martindale    Page : 1324   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Dipyridamole inhibits adenosine uptake and therefore may potentiate the action of adenosine; if use of the two drugs is essential the dosage of adenosine should be reduced. Theophylline and other xanthines are competitive antagonists of adenosine. The risk of AV block may be increased if adenosine is used with other drugs that slow AV conduction.,
Ref :-   Book : Martindale    Page : 1324   Edition : 37,


►  Contraindication : second -or- third degree AV block,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 421   Edition : 3,
  ►  Mechanism of Action :   Adenosine is an endogenous adenine nucleoside that is one of the components of nucleic acids and many coenzymes; as such, it is involved in many biological processes. It acts as an antiarrhythmic by stimulating adenosine A1-receptors and slowing conduction through the AV node. ,
Ref :-   Book : Martindale    Page : 1324   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Lily of the valley with Another pathway,

  ►  Pathway with its reference as follows :-
  • Cardenolides have Anti arrhythemic effect --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- GRAPE FRUIT with Grape fruit and Grape fruit juice can intreact with quinidine and decreases the level of quinidine in our body.,

      ►  Reference :-

  •   ►  URL -- ,

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :   Min value :-   >10 sec,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1324   Edition : 37,


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA