Alfuzosin is a Medicine belongs to Alpha blocker group whose information about Brand can be referenced from   Book : Martindale    Page : 2352   Edition : 38,

  ►   Brandname : Flotral,Besavar,Alfoo,UroXatral,Alfunar,WeiPing

  ►  Strength : Tablet with 10  Mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 166   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Basic & Clinical pharmacology    Page : 166   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Benign prostatic hyperplasia Oral 2.5 mg Tablet t.i.d.
2 Acute urinary retention Oral 10 mg Tablet o.d. For patients aged over 65 years catheterised for acute urinary retention associated with benign prostatic hyperplasia.

Ref :-  Book : Martindale    Page : 2384   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Orthostatic hypotension, tachycardia, Dizziness, drowsiness, headache, lack of energy, nausea, palpitations, oedema, chest pain, dyspepsia, constipation, diarrhea, vomiting, Depression, Nervousness, Sleep disturbances, vertigo, hallucinations, paraesthesia, nasal congestion, epistaxis, dry mouth, reddened sclera, Blurred Vision, tinnitus, abnormal liver enzyme values, Pancreatitis, arthralgia, alopecia, lichen planus, Skin rashes, pruritus, diaphoresis, Impotence, priapism, rhinitis, bronchitis, urinary frequency, urinary incontinence, upper respiratory-tract infections, angina, prolongation of the QT interval, jaundice, hepatocellular injury, cholestatic liver injury, ,
Ref :-   Book : Martindale    Page : 1510, 2354   Edition : 37,    Page :    Edition : ,

►  Drug Interaction : Drug interaction of Alfuzosin is with Diuretic Agents , Antihypertensive Agents , Alcohol, , Beta Blockers , Calcium Channel Blockers ,  Ketoconazole , Itraconazole , Ritonavir,
Ref :-   Book : Martindale    Page : 2384,1510   Edition : 37, Martindale    Page : 2384   Edition : 37, Martindale    Page :    Edition : ,


  ►    Mechanism of Drug Drug Interaction :  The hypotensive effects of prazosin may be enhanced by use with diuretics and other antihypertensives, and by alcohol and other drugs that cause hypotension. The risk of first-dose hypotension may be particularly increased in patients receiving beta blockers or calciumchannel blockers. Potent inhibitors of the cytochrome P450 isoenzyme CYP3A4, such as ketoconazole, itraconazole, and ritonavir, may increase blood concentrations of alfuzosin.,
Ref :-   Book : Martindale    Page : 1510   Edition : 37,


►  Contraindication : pre-existing ischaemic heart disease, Severe hepatic impairment,
Ref :-   Book : Martindale    Page : 2352   Edition : 38,
  ►  Mechanism of Action :   Alfuzosin is an alpha1-adrenoceptor blocker. It acts preferentially on receptors in the lower urinary tract and is therefore used in benign prostatic hyperplasia to relieve symptoms of urinary obstruction, including acute urinary retention.,
Ref :-   Book : Martindale    Page : 2384   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Lotus seed with Another pathway,

  ►  Pathway with its reference as follows :-
  • beneficial for benign prostatic hyperplasia --- (Duke, J. & Duke, J. (2002). Handbook of medicinal herbs. Boca Raton, FL: CRC Press. )

  •   ►  URL -- https://books.google.co.in/books?id=UcLYLpwdcm8C&pg=PA513&dq=Duke, +J.+%26+Duke, +J.+(2002).+Handbook+of+medicinal+herbs.+Boca+Raton, +FL:+CRC+Press.&hl=en&sa=X&redir_esc=y#v=onepage&q=Duke%2C%20J.%20%26%20Duke%2C%20J.%20(2002).%20Handbook%20,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- CATS CLAY with Do not take with diabetic drug adverse effect have been reported.,

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand.

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,

    ►   Route of Elimination :   Fecal, Hepatic (Metabolism), Renal,
    Ref :-   Book : Martindale    Page : 2384   Edition : 37,


    ►    Plasma Half-life :   Min value :-   3 hours,    Max value :-   5 hours,
    Ref :-   Book : Martindale    Page : 2384   Edition : 37,


    ►    Peak Plasma Concentration :   Min value :-   0.5 hours,    Max value :-   3 hours,
    Ref :-   Book : Martindale    Page : 2384   Edition : 37,