Aluminium hydroxide is a Medicine belongs to Gastrointestinal drug group whose information about Brand can be referenced from   Book :    Page :   Edition :    Martindale    Page : 1817   Edition : 38  

  ►   Brandname : Digecaine, digene, mucaine - gel , Aludrox, Tricaine-MPS, Alu-Cap, ALternaGEL, Antiphosphat
  ►  Strength : Tablet with 300 mg.  Tablet with 500 mg.  Tablet with 600 mg.  Capsule with 400 mg.  Capsule with 500 mg.  Oral Suspension with 320 mg/5mL.  Oral Suspension with 450 mg/5mL.  Oral Suspension with 675 mg/5mL. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 1111   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 1817   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 As an Antacid Oral Tablet It is given orally in doses of up to about 1 g, between meals and at bedtime. In order to reduce the constipating effects, aluminium hydroxide is often given with a magnesium-containing antacid, such as magnesium oxide or magnesium hydroxide.
2 Hyperphosphataemia in patients with chronic renal failure The dose must be adjusted to the individual patient’s requirement but up to about 10 g daily may be given orally in divided doses with meals.

Ref :-  Book : Martindale    Page : 1817   Edition : 38  

Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : May cause constipation, Large doses can cause intestinal obstruction, Excessive doses, or even normal doses in patients with low-phosphate diets, may lead to phosphate depletion accompanied by increased bone resorption and hypercalciuria with the risk of osteomalacia, If used as an adjuvant in adsorbed vaccines has been associated with the formation of granulomas
Ref :-   Book : Martindale    Page : 1817   Edition : 38.  

►  Drug Interaction : Drug interaction of Aluminium hydroxide is with , ,  NA

  ►    Mechanism of Drug Drug Interaction :  Aluminium compounds used as antacids interact with many other drugs, both by alterations in gastric pH and emptying, and by direct adsorption and formation of complexes that are not absorbed. Interactions can be minimised by giving the aluminium compound and any other medication 2 to 3 hours apart. The absorption of aluminium from the gastrointestinal tract may be enhanced if aluminium compounds are taken with citrates or ascorbic acid.
Ref :-   Book : Martindale    Page : 1818   Edition : 38.  

►  Contraindication : NA
  ►  Mechanism of Action :   Antacids are basic compounds that neutralise hydrochloric acid in the gastric secretions.
Ref :-   Book : Martindale    Page : 1803   Edition : 38.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- fennel seed with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Antacid effect . --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL --
  • .

  • DIETARY Substance Interactions

    ​   ► This Medicine interact with :- CALCIUM with Aluminum hydroxide may increase urinary and stool loss of calcium ..   CITRATE with Combination of citrate , either as calcium citrate supplements or from orange and lemon juice , with aluminum - containing antacids increases aluminum -containing antacids increases aluminum levels in the body.   FOLIC ACID with Aluminum hydroxide inhibit folic acid absorption ..   IRON with Dietary Substance is Drug Inhibitor.  

      ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand

  •   ►  URL --

    ContraIndication DIETARY Substance

    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Faecal, Renal
    Ref :-   Book : Martindale    Page : 1818   Edition : 38.  

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA