Amphetamine is a Medicine belongs to CNS Stimulant group whose information about Brand can be referenced from   Book : Martindale    Page : 2349   Edition : 37  

  ►   Brandname : Adderall
  ►  Strength : Tablet with 5 mg.  Tablet with 10 mg. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 148   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Basic & Clinical pharmacology    Page : 148   Edition : 12  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Narcolepsy Oral 5 10 mg Tablet Given daily in divided doses.

Ref :-  Book : Martindale    Page : 2316,2319   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Narcolepsy 6 Year 12 Year Oral 5 mg
2 Hyperactivity disorder 6 Year above 6 Year Oral 5 mg o.d/b.d

Ref :- Book : Martindale    Page : 2316,2319   Edition : 38  
►  Side Effect : Headache, Dizziness, Confusion, palpitations, Dysphoria, Agitation, Apprehension, Delirium, Fatigue, Vasomotor disturbances
Ref :-   Book : Goodman    Page : 298   Edition : 12.   Goodman    Page : 298   Edition : 12.  

►  Drug Interaction : Drug interaction of Amphetamine is with Antihypertensive Agents , Monoamine Oxidase Inhibitor, Beta Blockers ,  NA

  ►    Mechanism of Drug Drug Interaction :  Interactions are as expected from mode of action, e.g. antagonism of antihypertensives; severe hypertension with MAOIs and β-adrenocepter blocking drugs.
Ref :-   Book : Clinical Pharmacology    Page : 193   Edition : 9.  


►  Contraindication : Advanced cardiovascular disease, Glaucoma, Hyperthyroidism, MAOI therapy, Severe hypertension
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 147   Edition : 3.  
  ►  Mechanism of Action :   Amphetamine appears to exert most or all of its effects in the CNS by releasing biogenic amines from their storage sites in nerve terminals.
Ref :-   Book : Goodman    Page : 298   Edition : 12.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Tea with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Tea having active constituent caffeine which act as nervous system stimulant --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL --
  • http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- EPHEDRA with overstimulation ,nervousness ,heart arrhythmias ..  

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20

    ►   Route of Elimination :   Renal
    Ref :-   Book : Clinical Pharmacology    Page : 193   Edition : 9.  

    ►    Plasma Half-life :   Min value :-   12 hours ,    Max value :-   NA
    Ref :-   Book : Clinical Pharmacology    Page : 193   Edition : 9.  

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA