Anastrozole is a Medicine belongs to Antineoplastic group whose information about Brand can be referenced from   Book : Martindale    Page : 743   Edition : 38, Martindale    Page : 743   Edition : 38,

  ►   Brandname : Altraz,Armotraz,Arimidex,Anastrol,Anablock,Ai Da

  ►  Strength : Tablet with 1  Mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 740   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Basic & Clinical pharmacology    Page : 740   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Advanced or locally advanced breast cancer Oral 1 mg Tablet o.d. In postmenopausal women.
2 Adjuvant treatment in hormone receptor-positive early breast cancer Oral 1 mg Tablet o.d. in postmenopausal women.

Ref :-  Book : Martindale    Page : 744   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : anorexia, nausea, vomiting, diarrhea, asthenia, Dizziness, drowsiness, headache, Rashes, hair thinning, myalgia, arthralgia, bone fractures, abnormal liver enzyme values, thromboembolism, hot flashes, vaginal dryness or bleeding, increases in total cholesterol, insomnia, Depression, peripheral edema, lymphoedema, increased cough, hypertension, , Reductions in bone mineral density,
Ref :-   Book : Martindale    Page : 744   Edition : 37, Martindale    Page : 744   Edition : 37,    Page :    Edition : ,

►  Drug Interaction : Drug interaction of Anastrozole is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : premenopausal women (particularly in pregnancy),
Ref :-   Book : Martindale    Page : 744   Edition : 37,
  ►  Mechanism of Action :   Anastrozole is a potent and selective nonsteroidal inhibitor of the aromatase (oestrogen synthetase) system, which converts adrenal androgens to oestrogens in peripheral tissue,
Ref :-   Book : Martindale    Page : 744   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Soyabean with Another pathway, Aesculus glabra with same pathway, Agaricus bisporus with same pathway, Agaricus blazei with same pathway, Onion with same pathway, Red ginger with same pathway, Celery with same pathway, Asparagus with same pathway,

  ►  Pathway with its reference as follows :-
  • Soyabean having active constituent isoflavones which act as anticancer . --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )
  • Aromatase inhibitor --- ( Balunas M. Natural Products as Aromatase Inhibitors. PMCID. 2008;8(6):646-682. )
  • Aromatase inhibitor --- (Balunas M. Natural Products as Aromatase Inhibitors. PMCID. 2008;8(6):646-682. )
  • Aromatase inhibitor --- (Balunas M. Natural Products as Aromatase Inhibitors. PMCID. 2008;8(6):646-682. )
  • Aromatase inhibitor --- ( Balunas M. Natural Products as Aromatase Inhibitors. PMCID. 2008;8(6):646-682. )
  • Aromatase inhibitor --- (Balunas M. Natural Products as Aromatase Inhibitors. PMCID. 2008;8(6):646-682. )
  • Aromatase inhibitor --- (Balunas M. Natural Products as Aromatase Inhibitors. PMCID. 2008;8(6):646-682. )
  • Aromatase inhibitor --- (Balunas M. Natural Products as Aromatase Inhibitors. PMCID. 2008;8(6):646-682. )

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074486/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074486/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- ST JOHNS WORT with It decrease effect of the drug .,

      ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- http://www.otto-wipfel.co.uk/otto/supplements-medication/DRUG-HERB-VITAMINS-INTERACTIONS-A-Z_Guide.pdf,

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 744   Edition : 37,


    ►    Plasma Half-life :   Min value :-   40 hours,    Max value :-   50 hours,
    Ref :-   Book : Martindale    Page : 744   Edition : 37,


    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 744   Edition : 37,