Arginine or L-arginine is a Medicine belongs to Nutritional agents group whose information about Brand can be referenced from   Book : Martindale    Page : 2050   Edition : 38,

  ►   Brandname : R-Gene,Arginitric,Nitriga,Hua S hi Ai Er

  ►  Strength : Tablet with   , Capsule with   , Injection with   , Oral solution with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 2050   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV, Oral,
Reference :-   Book : Martindale    Page : 2049   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 For evaluation of growth disorders IV infusion 30 gm Injection It is used as a 10% solution of the hydrochloride; and given over 30 minutes.

Ref :-  Book : Martindale    Page : 2049   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 To treat or prevent deficiency or to aid recovery during convalescence Oral 1 gm Oral solution o.d/b.d
2 For evaluation of growth disorders less than 60 kg IV infusion 500 mg/kg Injection
3 For evaluation of growth disorders

Ref :- Book : Martindale    Page : 2049   Edition : 38,
►  Side Effect : nausea, vomiting, flushing, headache, Numbness, and local venous irritation may occur if arginine solutions are infused too rapidly, extravasation, burn like reaction, skin necrosis, Rashes, anaphylaxis, haematuria, rise in plasma potassium conc. in uraemic patients, isolated reports of a decrease in platelet count,
Ref :-   Book : Martindale    Page : 2085   Edition : 37,

►  Drug Interaction : Drug interaction of Arginine or L-arginine is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : treatment stopped if hypersensitivity reactions are seroius ,
Ref :-   Book : Martindale    Page : 2050   Edition : 38,
  ►  Mechanism of Action :   Arginine is a basic amino acid that is essential for infant growth. Arginine stimulates the release of growth hormone by the pituitary gland and may be used instead of, or in addition to, other tests such as insulin-induced hypoglycaemia, for the evaluation of growth disorders.,
Ref :-   Book : Martindale    Page : 2085   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- peanut with same compound, walnut with same compound,

  ►  Pathway with its reference as follows :-
  • Arginine --- (.Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart )
  • rich in arginine --- (Hu, F. (2003). Plant-based foods and prevention of cardiovascular disease: an overview1,2,3,4. The American Journal Of Clinical Nutrition. )

  •   ►  URL -- http://197.14.51.10:81/pmb/AGROALIMENTAIRE/Handbook%20of%20Nutrition.pdf, http://ajcn.nutrition.org/content/78/3/544S.full,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- ALFALFA with Alfalfa contain toxic compound canavanine ,which is a structure analogue of arginine & interfere with arginine function .y,

      ►  Reference :-
  • Driver, S. (2009). Stockleys Herbal Medicines Interactions. Royal pharmaceutical Society of Great Britain: Pharmaceutical press.

  •   ►  URL -- https://www.stonybrookmedicine.edu/sites/default/files/herbal_medicines_interactions-1.pdf,

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA