Atenolol is a Medicine belongs to Beta Blockers group whose information about Brand can be referenced from   Book : Martindale    Page : 1341   Edition : 37  

  ►   Brandname : Atecard, Aten, Beten, Antipressan, Atenix, Tenormin, Anselol, Ate Lich
  ►  Strength : Tablet with 25 Mg.  Tablet with 50 Mg.  Tablet with 100 Mg.  Injection with 0.5 mg/ml.  Oral solution with

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 166   Edition : 12   Martindale    Page : 1341   Edition : 37  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV
Reference :-   Book : Martindale    Page : 1341   Edition : 37  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 hypertension Oral 25 100 mg Tablet o.d.
2 Angina pectoris Oral 50 100 mg Tablet given daily as a single dose or in divided doses.
3 Emergency treatment of cardiac arrhythmias IV 2.5 10 mg Injection injected at a rate of 1 mg/minute.
4 Acute myocardial infarction slow i.v 5 10 mg Injection Treatment given within 12 hours of the onset of chest pain; given at a rate of 1 mg/minute.
5 Prophylaxis of migraine Oral 50 200 mg Tablet given daily.

Ref :-  Book : Martindale    Page : 1308   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Cardiac arrhythmias Oral 0.5 1 mg/kg/day Oral solution

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1611   Edition : 19  
Precaution :- If a Patient is using 'Atenolol' drug in  MYASTHENIA GRAVIS  disease, then Please Use with caution .

Precaution :- If a Patient is using 'Atenolol' drug in  acute severe asthma  disease, then Please avoid giving ACE inhibitors,B blockers..are triggers. .

►  Side Effect : Bradyarrhythmia, Atrioventricular block, Less bronchospasm, Sedation, Decreased libido, Depression, Dyspnoea, Wheezing, Masks symptom of hypoglycemia
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 146   Edition : 3.  

►  Drug Interaction : Drug interaction of Atenolol is with Angiotensin converting enzyme inhibitor, Calcium Channel Blockers , Antiarrhythmics, ,  Clonidine , Verapamil , Digoxin
Ref :-   Book : Martindale    Page : 1321   Edition : 38.  


  ►    Mechanism of Drug Drug Interaction :  Drugs that enhance the antihypertensive effects of beta blockers, such as ACE inhibitors, calcium-channel blockers, and clonidine may be useful in controlling hypertension. Use of beta blockers with other cardiac depressants such as antiarrhythmics and rate-limiting calciumchannel blockers can precipitate bradycardia and heart block; the combination of intravenous verapamil and beta blockers should especially be avoided. Beta blockers may potentiate bradycardia due to digoxin.
Ref :-   Book : Martindale    Page : 1321   Edition : 38.  


►  Contraindication : Cardiogenic shock, Decompensated cardiac failure, Second and third degree AV block, Severe sinus bradycardia, Bronchial asthma or chronic obstructive pulmonary disease
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 146   Edition : 3.  
  ►  Mechanism of Action :   Atenolol is a cardioselective beta 1 blocker It is reported to lack intrinsic sympathomimetic activity and membrane-stabilising properties.
Ref :-   Book : Martindale    Page : 1341   Edition : 37.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Guava with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Vasodilators. --- (Anti-hypertensive effect of pink guava (Psidium guajava) puree on spontaneous hypertensive rats. (2016). International Food Research Journal, 17, 89-96. )

  •   ►  URL --
  • http://www.ifrj.upm.edu.my/17%20(01)%202010/(10)%20IFRJ-2010-89-96%20Norazmir.pdf .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- CASTOR with Increase effect due to potassium loss with chronic use of herb..   PLEURISY ROOT with It contain glycosides , it is best to avoid use of pleurisy root with heart medication such as atenolol ..  

      ►  Reference :- NA
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- https://www.stonybrookmedicine.edu/sites/default/files/herbal_medicines_interactions-1.pdf
    http://www.otto-wipfel.co.uk/otto/supplements-medication/DRUG-HERB-VITAMINS-INTERACTIONS-A-Z_Guide.pdf

    ►   Route of Elimination :   Hepatic (Metabolism), Renal
    Ref :-   Book : Martindale    Page : 1341   Edition : 37.  

    ►    Plasma Half-life :   Min value :-   6 hours,    Max value :-   7 hours.  
    Ref :-   Book : Martindale    Page : 1341   Edition : 37.  

    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   4 hours.  
    Ref :-   Book : Martindale    Page : 1341   Edition : 37.