Bacitracin is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 225   Edition : 38,

  ►   Brandname : Baci-IM

  ►  Strength : Ointment with   , Ophthalmic Ointment with   , Injection with   , Cream with   , dusting powder with   , Solution with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 226   Edition : 38, Basic & Clinical pharmacology    Page : 805   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical, IM,
Reference :-   Book : Martindale    Page : 226   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Suppression of mixed bacterial flora in surface lesions Topical 500 units/gm Ointment Used on lesions of the skin, in wounds, or on mucous membranes.
2 Irrigation of joints and wounds 100 200 units/ml Solution
3 Irrigation of the pleural cavity 100 200 units/ml Solution

Ref :-  Book : Basic & Clinical pharmacology    Page : 805   Edition : 12,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Staphylococcal pneumonia and empyema less than 2.5 kg IM 900 units/kg Injection
2 Staphylococcal pneumonia and empyema more than 2.5 kg IM 1000 units/kg Injection

Ref :- Book : Martindale    Page : 226   Edition : 38,
►  Side Effect : nephrotoxicity, neurotoxicity, Bone marrow suppression, Contact dermatitis, Blurred Vision, red eye,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 614   Edition : 3,

►  Drug Interaction : Drug interaction of Bacitracin is with Neuromuscular blocking drugs , Anaesthetics,  Colistin, Kanamycin , Neomycin , Polymyxin B, Streptomycin ,
Ref :-   Book : Martindale    Page : 226   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Additive nephrotoxicity would be anticipated if bacitracin were given systemically with other nephrotoxic drugs, particularly colistin, kanamycin, neomycin, polymyxin B, and streptomycin; such use should be avoided. Bacitracin is reported to enhance the neuromuscular blocking action of certain drugs, such as neuromuscular blockers and anaesthetics, if given during surgery or postoperatively.,
Ref :-   Book : Martindale    Page : 226   Edition : 38,


►  Contraindication : (incase of oral bacitracin) co-administration with nephrotoxic agents or neuromuscular blocking agents,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 614   Edition : 3,
  ►  Mechanism of Action :   Bacitracin inhibits cell wall formation by interfering with dephosphorylation in cycling of the lipid carrier that transfers peptidoglycan subunits to the growing cell wall. There is no cross-resistance between bacitracin and other antimicrobial drugs.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 805   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Pomegranate with Another pathway,

  ►  Pathway with its reference as follows :-
  • It increasing the rate of wound healing. --- (Howell, A. & D'Souza, D. (2013). The Pomegranate: Effects on Bacteria and Viruses That Influence Human Health. Evidence-Based Complementary And Alternative Medicine, 2013, 1-11. doi:10.1155/2013/606212 )

  •   ►  URL -- https://www.hindawi.com/journals/ecam/2013/606212/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 225   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA