Betaxolol is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1323   Edition : 38,

  ►   Brandname : Optipres,Betoptic,Bulol,Kerlone,Betoptima,Kerlong

  ►  Strength : Tablet with 10  Mg, Tablet with 20  Mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 189   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, Topical,
Reference :-   Book : Martindale    Page : 1355   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 hypertension Oral 10 mg Tablet o.d.
2 Open-angle glaucoma Topical 0.25 0.5 % Eye Drop b.d. Also these doses are given in Ocular hypertension.
3 Angina pectoris Oral 10 mg Tablet o.d.

Ref :-  Book : Martindale    Page : 1355   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Glaucoma

Ref :- Book : Martindale    Page : 1322   Edition : 38,
►  Side Effect : Less bronchospasm, decreased libido, Sedation, Depression, masks symptom of hypoglycemia, dyspnoea, wheezing, atrioventricular block,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 146   Edition : 3,

►  Drug Interaction : Drug interaction of Betaxolol is with Antiarrhythmics, Oral Hypoglycemic Drugs, , , Barbiturates , Angiotensin converting enzyme inhibitor, Calcium Channel Blockers , General anaesthetics , NONSTEROIDAL ANTI-INFLAMMATORY DRUGS,  Rifampicin , Cimetidine , Erythromycin , Fluvoxamine, Hydralazine , Verapamil , Digoxin , Insulin , Clonidine , Aldesleukin ,
Ref :-   Book : Martindale    Page : 1352   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Drugs that enhance the antihypertensive effects of beta blockers, such as ACE inhibitors, calcium-channel blockers, and clonidine may be useful in controlling hypertension. Drugs that cause hypotension such as aldesleukin and general anaesthetics also enhance the antihypertensive effects of beta blockers while other drugs, for example NSAIDs, antagonise the antihypertensive effects. Use of beta blockers with other cardiac depressants such as antiarrhythmics and rate-limiting calcium channel blockers can precipitate bradycardia and heart block; the combination of intravenous verapamil and beta blockers should especially be avoided. Beta blockers may potentiate bradycardia due to digoxin. In diabetic patients beta blockers can reduce the response to insulin and oral hypoglycaemics through their effects on pancreatic beta receptors. Drugs that reduce absorption include aluminium salts and bile-acid binding resins such as colestyramine. Metabolism of some beta blockers can be increased by drugs such as barbiturates and rifampicin and decreased with drugs such as cimetidine, erythromycin, fluvoxamine, and hydralazine. Drugs that alter hepatic blood flow also affect metabolism of some beta blockers. For example, cimetidine and hydralazine decrease hepatic blood flow and this contributes to the decreased hepatic clearance seen with these drugs. Drugs that influence hepatic metabolism affect beta blockers that are extensively metabolised, such as labetalol, propranolol, and timolol, while beta blockers that are excreted largely unchanged, for example atenolol and nadolol, are unaffected. Since systemic absorption can occur after ocular use of beta blockers the possibility of similar interactions should be considered.,
Ref :-   Book : Martindale    Page : 1321   Edition : 38,


►  Contraindication : bronchial asthma or chronic obstructive pulmonary disease, cardiogenic shock, Decompensated cardiac failure, Second and third degree AV block, Severe sinus bradycardia,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 146   Edition : 3,
  ►  Mechanism of Action :   Betaxolol is a cardioselective beta blocker It is reported to lack intrinsic sympathomimetic activity and to have little membrane-stabilising activity.,
Ref :-   Book : Martindale    Page : 1322   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal, breast milk, Hepatic (Metabolism),
Ref :-   Book : Martindale    Page : 1355   Edition : 37,


►    Plasma Half-life :
  Min value :-   14 hours,    Max value :-   22 hours,
Ref :-   Book : Martindale    Page : 1355   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,