Butobarbitone/ Butobarbital is a Medicine belongs to Hypnotic group whose information about Brand can be referenced from   Book : Martindale    Page : 1070   Edition : 37,

  ►   Brandname : Soneryl

  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1064   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Severe intractable insomnia Oral 100 200 mg h.s.

Ref :-  Book : Martindale    Page : 1044   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : drowsiness, Sedation, ataxia, respiratory depression, headache, gastrointestinal disturbance, Confusion, megaloblastic anaemia, , Abnormal thinking, Paradoxical excitement and irritability may occur, particularly in children, the elderly, and patients in acute pain,
Ref :-   Book : Martindale    Page : 1038,1044    Edition : 38,    Page :    Edition : ,

►  Drug Interaction : Drug interaction of Butobarbitone/ Butobarbital is with , Alcohol, , Monoamine Oxidase Inhibitor, ,  NA

  ►    Mechanism of Drug Drug Interaction :  Sedation or respiratory depression may be enhanced by drugs with CNS-depressant properties; in particular alcohol should be avoided. Barbiturates generally induce liver enzymes, and thus increase the rate of metabolism (and decrease the activity) of many other drugs as well as endogenous substances. Continued use may result in induction of their own metabolism. MAOIs may prolong the CNS depressant effects of some barbiturates, probably by inhibition of their metabolism.,
Ref :-   Book : Martindale    Page : 1038,1044   Edition : 38,


►  Contraindication : children, Elderly and debilitated patient, young adult, In those with depression or a history of drug or alcohol addiction or abuse, patients affected should not drive or operate machinery,
Ref :-   Book : Martindale    Page : 1038,1044   Edition : 38,
  ►  Mechanism of Action :   Bind to specific GABAA receptor subunits at CNS neuronal synapsis increasing duration of GABA mediated chloride ion channel opening, enhance membrane hyperpolarization.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 386   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA