Cabergoline is a Medicine belongs to Endocrine drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 900   Edition : 38, Martindale    Page : 900   Edition : 38,

  ►   Brandname : Caberlin,Camforte,Cabaser,Dostinex,CB-Lin,Parcar

  ►  Strength : Tablet with 0.5  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 678   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 899   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Suppression of established lactation Oral 250 Microgram Tablet b.d. For 2 days.
2 Inhibit physiological lactation Oral 1 mg Tablet Single dose on the first day post partum.
3 Hyperprolactinaemia Oral 500 micrograms Tablet Weekly.
4 Parkinson’s disease Oral 500 micrograms Tablet Daily in monotherapy.
5 Parkinson’s disease Oral 1 mg Tablet In adjunctive therapy.

Ref :-  Book : Martindale    Page : 899   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : nausea, erythromelalgia, prolonged severe hypotension, arrhythmia, exacerbation of angina, retroperitoneal fibrosis, pleural effusion, pericarditis, pericardial effusion, headache, nasal congestion, drowsiness, constipation, diarrhea, altered liver function tests, dyskinesia, psychomotor excitation, gastrointestinal bleeding, vomiting, Dizziness, Orthostatic hypotension, hypertension,
Ref :-   Book : Martindale    Page : 900,896   Edition : 38,

►  Drug Interaction : Drug interaction of Cabergoline is with Phenothiazine, Butyrophenone, Thioxanthenes , Metoclopramide , Memantine hydrochloride , Octreotide ,
Ref :-   Book : Martindale    Page : 900,899   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Dopamine antagonists such as the phenothiazines, butyrophenones, thioxanthenes, and metoclopramide might be expected to reduce the prolactin- lowering and the antiparkinsonian effects of Cabergoline and domperidone might reduce its prolactin- lowering effect. Memantine may enhance the effects of Cabergoline. Stimulants of gastrointestinal motility such as macrolide antibacterials or octreotide can increase the bioavailability of Cabergoline.,
Ref :-   Book : Martindale    Page : 900,899   Edition : 38,


►  Contraindication : Uncontrolled hypertension, Hypersensitivity to ergot derivatives,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 478   Edition : 3,
  ►  Mechanism of Action :   Inhibit pitutary prolactin release.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 478   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Fava beans i.e. bakla with same compound,

  ►  Pathway with its reference as follows :-
  • Fava beans rich in levo-dihydroxyphenylalanine(L-Dopa) the precursor of dopamine. --- (Mehran S.M., Mohseni. "Simultaneous Determination Of Levodopa And Carbidopa From Fava Bean, Green Peas And Green Beans By High Performance Liquid Gas Chromatography". JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (2013): n. pag. Web. 10 Nov. 2016. )

  •   ►  URL -- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708185/,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- AGNUS CASTUS I.E. NIRGANDHI with Nirgandhi interact with dopamine agonist drug,

      ►  Reference :-
  • Driver, S. (2009). Stockleys Herbal Medicines Interactions. Royal pharmaceutical Society of Great Britain: Pharmaceutical press.

  •   ►  URL -- https://www.stonybrookmedicine.edu/sites/default/files/herbal_medicines_interactions-1.pdf,

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 900   Edition : 38,


    ►    Plasma Half-life :   Min value :-   63 hours,    Max value :-   68 hours,
    Ref :-   Book : Martindale    Page : 900   Edition : 38,


    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   3 hours,
    Ref :-   Book : Martindale    Page : 900   Edition : 38,