Calcitonin is a Medicine belongs to Thyroid hormone group whose information about Brand can be referenced from   Book : Martindale    Page : 1180   Edition : 38,

  ►   Brandname : Miacalcic,Zycalcit,Calsynar,Calcimar,Fortical,Miacalcin,Osteocalcin,Biocalcin,Calcinase,Ostospray

  ►  Strength : Nasal Spray with 200  IU/puff, Injection with 200  IU/ml, Nasal solution with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 786   Edition : 12, Martindale    Page : 1180   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM, IV, rectal, SC, nasal,
Reference :-   Book : Martindale    Page : 1178   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Paget’s disease s.c/ i.m 50 units Injection t.i.w.
2 Hypercalcaemia s.c/ i.m 4 units/kg Injection b.d.
3 Acute bone loss s.c/ i.m 100 units Injection o.d.
4 Postmenopausal osteoporosis nasal 200 units Nasal Spray Daily.
5 Hypercalcaemic crisis IV infusion 10 units/kg Injection Diluted in 500 mL of sodium chloride 0.9% and given by slow intravenous infusion over at least 6 hours.

Ref :-  Book : Martindale    Page : 1178   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
Precaution :- If a Patient is using 'Calcitonin' drug in  hypothyroidism  disease, then Please be used with caution .

►  Side Effect : nausea, vomiting, diarrhea, Dizziness, flushing, tingling of the hands, Skin rashes, unpleasant taste, abdominal pain, urinary frequency, tremor, transient hypocalcaemia, diabetogenic effect, Hyperphosphataemia, hypercalcemia,
Ref :-   Book : Martindale    Page : 1179   Edition : 38, Martindale    Page : 2117   Edition : 38,

►  Drug Interaction : Drug interaction of Calcitonin is with Cardiac Glycosides, Calcium Channel Blockers ,  NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Hypocalcaemia,
Ref :-   Book : Martindale    Page : 1179   Edition : 38,
  ►  Mechanism of Action :   Calcitonin binds to and activates a G Protein –coupled receptor on osteoclasts thereby decreasing the resorptive activity of these cells.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 555   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- VITAMIN C with Increase in Nutrient Level,

  ►  Reference :-
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- MAGNESIUM with Reduces urinary magnesium excretion., CALCIUM with Decreases calcium release from bone. ,

      ►  Reference :-
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf,

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 1179   Edition : 38,


    ►    Plasma Half-life :   Min value :-   16 min,    Max value :-   43 min,
    Ref :-   Book : Martindale    Page : 1179   Edition : 38,


    ►    Peak Plasma Concentration :   Min value :-   30 min,    Max value :-   40 min,
    Ref :-   Book : Martindale    Page : 1179   Edition : 38,