Calcium / Calcium gluconate is a Medicine belongs to Electrolytes group whose information about Brand can be referenced from   Book : Martindale    Page : 1786   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Calcium-Sandoz,Phosforid,BioCalth,Ostram,Phos-Ex,Sandocal,Cal-C,Cal-Citrate,Cal-G,Cal-Lac,Calphron,Citracal,Oyster Calcium,PhosLo,Posture,A to Z,Calcimax,Calcimax Forte,Calvit,Calvit Lc,Becosule,Ostocalcium

  ►  Strength : Tablet with 500  Mg, Tablet with 650  Mg, Tablet with 975  Mg, Tablet with 1  gm, Injection with 10  %,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 786   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV, SC, IM, Topical,
Reference :-   Book : Martindale    Page : 1784   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Severe acute hypocalcaemia IV 2.25 4.5 mmol Injection slow i.v injection, either repeated as required,
2 Hypocalcaemic tetany IV 2.25 4.5 mmol Injection slow i.v injection, either repeated as required
3 Severe hyperkalaemia IV 10 20 mL Injection given mL of calcium gluconate in 10% conc. is used.
4 Severe hypermagnesaemia IV 10 20 mL Injection given mL of calcium gluconate in 10% conc. used.
5 Deficiency states Oral 10 50 mmol Tablet

Ref :-  Book : Martindale    Page : 1784, 1785   Edition : 38, Martindale    Page : 1785   Edition : 38, Martindale    Page : 1784   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Neonatal tetany IV injection 1 3 mg/kg

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1919   Edition : 19,
►  Side Effect : gastrointestinal irritation, necrosis of the skin, hypercalcaemia, anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disturbances, polydipsia, polyuria, nephrocalcinosis, renal calculi, chalky taste, hot flushes, peripheral vasodilatation, cardiac arrhythmia, coma, sloughing,
Ref :-   Book : Martindale    Page : 1786   Edition : 38,

►  Drug Interaction : Drug interaction of Calcium / Calcium gluconate is with Thiazide Diuretics , , Corticosteroid , Bisphosphonates, FLUOROQUINOLONES ,  Vitamin D, Corticosteroids, digitalis, Tetracycline ,
Ref :-   Book : Martindale    Page : 1786   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Vitamin D increases the gastrointestinal absorption of calcium and thiazide diuretics decrease its urinary excretion. Bran decreases the gastrointestinal absorption of calcium. Corticosteroids also reduce calcium absorption. Calcium enhances the effects of digitalis glycosides on the heart. Calcium salts reduce the absorption of a number of other drugs such as bisphosphonates, fluoroquinolones, and tetracyclines; doses should be separated by at least 3 hours.,
Ref :-   Book : Martindale    Page : 1786   Edition : 38,


►  Contraindication : renal impairment, Diseases associated with hypercalcaemia such as sarcoidosis and some malignancies, be avoided in patients with calcium renal calculi, or a history of renal calculi.,
Ref :-   Book : Martindale    Page : 1786   Edition : 38,
  ►  Mechanism of Action :   It is essential for bone mineralization.,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 561   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Milk & milk products with same compound,

  ►  Pathway with its reference as follows :-
  • Nutritional Supplement --- (Gopalan, C. (2012). Nutritive value of Indian foods. National Institute of Nutrition ,ICMR.: Hyderabad 500007,INDIA. )

  •   ►  URL -- http://www.eeb.cornell.edu/biogeo/nanc/Food_Feed/table%201%20gopalan%20et%20al%201989.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 1786   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA