Calcium Polystyrene Sulfonate is a Medicine belongs to Chelators Antidotes and Antagonists group whose information about Brand can be referenced from   Book : Martindale    Page : 1541   Edition : 38,

  ►   Brandname : Calcium Resonium,K-Bind,Sorbisterit,Kapstat

  ►  Strength : Suspension with   , Syrup with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1541   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, nasogastric, rectal,
Reference :-   Book : Martindale    Page : 1541   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Hyperkalaemia Oral 15 gm t.i.d/q.i.d Given as a syrup or suspension.

Ref :-  Book : Martindale    Page : 1541   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Hyperkalaemia Oral 1 gm/kg

Ref :- Book : Martindale    Page : 1541   Edition : 38,
►  Side Effect : hypercalcaemia, anorexia, nausea, vomiting, diarrhea, faecal impaction, bleeding, ulceration, ischaemic colitis, calcium overloading, gastrointestinal concretions, Intestinal necrosis , perforation,
Ref :-   Book : Martindale    Page : 1541, 1575   Edition : 38,

►  Drug Interaction : Drug interaction of Calcium Polystyrene Sulfonate is with , Cardiac Glycosides,  Aluminium hydroxide, Calcium carbonate , Levothyroxine, Felbamate, Loratadine,
Ref :-   Book : Martindale    Page : 1541   Edition : 38, Martindale    Page : 1576   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  When given orally with cation-donating antacids and laxatives such as magnesium hydroxide, aluminium hydroxide, or calcium carbonate, competition for binding sites may reduce the potassium-lowering effect of the resin. Seizures have been reported due to metabolic alkalosis in a patient given magnesium hydroxide with sodium polystyrene sulfonate. Ion-exchange resins may also bind other drugs, reducing their absorption. Drugs that have been affected include levothyroxine and lithium salts. Hypokalaemia may exacerbate the adverse effects of digoxin and sodium polystyrene sulfonate should be used with caution in patients receiving cardiac glycosides.,
Ref :-   Book : Martindale    Page : 1541   Edition : 38,


►  Contraindication : Hyperparathyroidism, Multiple myeloma, Hypokalemia, hypercalcaemia,
Ref :-   Book : Martindale    Page : 1541   Edition : 38,
  ►  Mechanism of Action :   Calcium polystyrene sulfonate, the calcium salt of sulfonated styrene polymer, is a cation-exchange resin that exchanges calcium ions for potassium ions and other cations in the gastrointestinal tract. ,
Ref :-   Book : Martindale    Page : 1541   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA