Calcium carbonate is a Medicine belongs to Gastrointestinal drug group whose information about Brand can be referenced from   Book : Martindale    Page : 1825   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Adcal,Cacit,Calcichew,Rap-eze,Remegel,Rennie Soft Chews,Sandocal,Sea-Cal,Setlers,Titralac,Tums,Alka-Mints,Alkets,Calcium-Sandoz,Calcicip,Calibon-Z,Calcium Iso,Calcitab,Caldikind,Gembone,Gemcal,Shelcal,Tayo

  ►  Strength : Tablet with 350  Mg, Tablet with 420  Mg, Tablet with 500  Mg, Tablet with 650  Mg, Tablet with 750  Mg, Tablet with 1000  Mg, Tablet with 1250  Mg, Suspension with 1250/5  mg/ml, Tablet with 600  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 1111   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1824   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Antacid Oral 1.5 gm Tablet
2 Hyperparathyroidism Oral 3 7 gm Tablet Daily in divided doses.

Ref :-  Book : Martindale    Page : 1824   Edition : 38, Martindale    Page : 1824   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 As phosphate binder in children with renal failure 1 Month 1 Year Oral 120 mg t.i.d/q.i.d
2 As phosphate binder in children with renal failure 1 Year 6 Year Oral 300 mg t.i.d/q.i.d
3 As phosphate binder in children with renal failure 6 Year 12 Year Oral 600 mg t.i.d/q.i.d
4 As phosphate binder in children with renal failure 12 Year 18 Year Oral 1.25 gm t.i.d/q.i.d
5 Hyperphosphataemia 1 Month 1 Year Oral 120 mg t.i.d/q.i.d
6 Hyperphosphataemia 1 Year 6 Year Oral 300 mg t.i.d/q.i.d
7 Hyperphosphataemia 6 Year 12 Year Oral 600 mg t.i.d/q.i.d
8 Hyperphosphataemia 12 Year 18 Year Oral 1.25 gm t.i.d/q.i.d

Ref :- Book : Martindale    Page : 1825   Edition : 38,
►  Side Effect : constipation, Flatulence, gastric hypersecretion, acid rebound, hypercalcaemia, alkalosis, milk-alkali syndrome, tissue calcification,
Ref :-   Book : Martindale    Page : 1825   Edition : 38,

►  Drug Interaction : Drug interaction of Calcium carbonate is with Thiazide Diuretics , , Corticosteroid , FLUOROQUINOLONES , Bisphosphonates,  Vitamin D, digitalis, Tetracycline ,
Ref :-   Book : Martindale    Page : 1824,1786   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Vitamin D increases the gastrointestinal absorption of calcium and thiazide diuretics decrease its urinary excretion. Bran decreases the gastrointestinal absorption of calcium, and may therefore decrease the efficacy of calcium supplements. Corticosteroids also reduce calcium absorption. Calcium enhances the effects of digitalis glycosides on the heart. Calcium salts reduce the absorption of a number of other drugs such as bisphosphonates, fluoroquinolones, and tetracyclines; doses should be separated by at least 3 hours,
Ref :-   Book : Martindale    Page : 1824,1786   Edition : 38,


►  Contraindication : renal impairment, hypercalcaemia, malignancy, acidosis,
Ref :-   Book : Martindale    Page : 1825,1786   Edition : 38,
  ►  Mechanism of Action :   Calcium carbonate binds phosphate in the gastrointestinal tract to form insoluble complexes and reduces phosphate absorption. ,
Ref :-   Book : Martindale    Page : 1824   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Milk & milk products with same compoundsame compound, Milk & milk products with same compoundsame compound,

  ►  Pathway with its reference as follows :-
  • Calcium --- (Gopala,C(2007) , Nutritive Value of Indian food , Hyderabad ;Indian Council of medical research )
  • nutritional supplements --- (Gopalan, C. (2012). Nutritive value of Indian foods. National Institute of Nutrition ,ICMR.: Hyderabad 500007,INDIA. )
  • Calcium --- (Gopala,C(2007) , Nutritive Value of Indian food , Hyderabad ;Indian Council of medical research )
  • nutritional supplements --- (Gopalan, C. (2012). Nutritive value of Indian foods. National Institute of Nutrition ,ICMR.: Hyderabad 500007,INDIA. )

  •   ►  URL -- https://books.google.co.in/books/about/Nutritive_Value_of_Indian_Foods.html?id=biFBAAAAYAAJ, http://www.eeb.cornell.edu/biogeo/nanc/Food_Feed/table%201%20gopalan%20et%20al%201989.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- IRON with Dietary Substance is Drug Inhibitor,

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal,
    Ref :-   Book : Martindale    Page : 1825   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA