Carbachol is a Medicine belongs to antiglaucoma drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 2005   Edition : 38  

  ►   Brandname : Carbastat, Miostat, Carbamann
  ►  Strength : Ophthalmic Solution with 0.01 %.  Ophthalmic Solution with 0.75 %.  Ophthalmic Solution with 1.5 %.  Ophthalmic Solution with 2.25 %.  Ophthalmic Solution with 3 %.  Eye Drop with

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 112   Edition : 12   Martindale    Page : 2005   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Intraocularly, Topical
Reference :-   Book : Martindale    Page : 2005   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Glaucoma Intraocularly Up to 3 % Eye Drop t.i.d. With other miotics.

Ref :-  Book : Martindale    Page : 2005   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition :   
►  Side Effect : Ciliary Spasm, Ocular pain, Irritation, Blurred Vision, Lachrymation, Myopia, Browache, Conjunctival vascular congestion, Superficial keratitis, Vitreous haemorrhage, Increased pupillary block
Ref :-   Book : Martindale    Page : 2005,2011   Edition : 38.  

►  Drug Interaction : Drug interaction of Carbachol is with Non Sterodial Anti- Inflammatory Drugs ,  NA

  ►    Mechanism of Drug Drug Interaction :  Carbachol ineffective when used in patients treated with topical (ophthalmic) NSAIDs.
Ref :-   Book : Martindale    Page : 2005   Edition : 38.  


►  Contraindication : Contra-indicated in conditions where pupillary constriction is undesirable such as acute iritis, acute uveitis, anterior uveitis, and some forms of secondary glaucoma. They should be avoided in acute inflammatory disease of the anterior segment of the eye., Extreme caution in patients with a history of retinal detachment and in young patients with myopia, Caution is necessary with night driving or when hazardous tasks are undertaken in poor illumination., Miotics should not be used by patients wearing soft contact lenses.
Ref :-   Book : Martindale    Page : 2005,2011   Edition : 38.  
  ►  Mechanism of Action :   Stimulate muscarinic receptor activity.
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 129   Edition : 3.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Calabar beans with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Useful in the treatment of glaucoma . --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL --
  • http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA