Carboplatin is a Medicine belongs to Antineoplastic group whose information about Brand can be referenced from   Book : Martindale    Page : 760   Edition : 38,

  ►   Brandname : Paraplatin,Bobei,Axicarb,Biocarb,Blastocarb

  ►  Strength : Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 760   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 759   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Ovarian cancers IV infusion 400 mg/m2 Injection
2 Small cell carcinoma of lung IV infusion 400 mg/m2 Injection

Ref :-  Book : Martindale    Page : 759   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Myelosuppression, nephrotoxicity, Gastrointestinal toxicity,
Ref :-   Book : Martindale    Page : 759   Edition : 38,

►  Drug Interaction : Drug interaction of Carboplatin is with Docetaxel,
Ref :-   Book : Martindale    Page : 760   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  When used with Docetaxel, clearance of carboplatin has been reported to be about 50% higher than values reported for carboplatin monotherapy.,
Ref :-   Book : Martindale    Page : 760   Edition : 38,


►  Contraindication : Creatinine clearance is 20 mL/minute or less,
Ref :-   Book : Martindale    Page : 759   Edition : 38,
  ►  Mechanism of Action :   Forms intrastrand and interstrand DNA cross-links; binding to nuclear and cytoplasmic proteins.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 956   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Cancer tree with Another pathway, Angeer with Another pathway,

  ►  Pathway with its reference as follows :-
  • Camptotecin have anticancer effect. --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )
  • 6-o-acyl-beta-d-glucosyl-beta-sitosterols.found in fig or anjeer have anticancer property. --- (Joseph, Baby. "Pharmacognostic And Phytochemical Properties Of Ficus Carica Linn –An Overview". International Journal of PharmTech Research 3.1 (2017): 08-12,. Print. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html, http://sphinxsai.com/Vol.3No.1/pharm_jan-mar11/pdf/JM11(%20PT=03)%2008-12.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- POTASSIUM with Increases urinary mineral excretion., MAGNESIUM with Increases urinary mineral excretion.,

      ►  Reference :-
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart

  •   ►  URL -- http://197.14.51.10:81/pmb/AGROALIMENTAIRE/Handbook%20of%20Nutrition.pdf,

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 764   Edition : 37,


    ►    Plasma Half-life :   Min value :-   6 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 760   Edition : 38,


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA