Carboprost is a Medicine belongs to Obstetric Drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 2133   Edition : 38  

  ►   Brandname : Deviprost, Prostodin, Hemabate,
  ►  Strength : Injection with .  Pessary with

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 328   Edition : 12   Martindale    Page : 2133   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IM, Vaginal
Reference :-   Book : Martindale    Page : 2133   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Termination of second trimester pregnancy (between 13 and 20 weeks of gestation) IM 250 micrograms Injection Every 11⁄2 to 31⁄2 hours depending on the uterine response. If necessary the dose may be increased to 500 micrograms, but the total dose given should not exceed 12 mg, and continuous use for more than 2 days is not recommended. It has also been given intra-amniotically in a dose equivalent to 1 mg of carboprost over five minutes; this dose may be repeated after 24 hours.
2 Postpartum haemorrhage IM 250 micrograms Injection If necessary the dose may be repeated at intervals of about 90 minutes.

Ref :-  Book : Martindale    Page : 2133   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition :   
Precaution :- If a Patient is using 'Carboprost' drug in  post partum haemorrhage  disease, then Please Contraindication: Asthmatics .

►  Side Effect : Bronchospasm, Dysphonia, Pulmonary oedema
Ref :-   Book : Martindale    Page : 2133   Edition : 38.  

►  Drug Interaction : Drug interaction of Carboprost is with Non Sterodial Anti- Inflammatory Drugs ,  Oxytocin , Aspirin
Ref :-   Book : Martindale    Page : 2133,2136   Edition : 38.  


  ►    Mechanism of Drug Drug Interaction :  Carboprost enhances the effects of oxytocin on the uterus. There is a theoretical risk that prostaglandin synthetase inhibitors, such as aspirin and NSAIDs, might alter the efficacy of Carboprost.
Ref :-   Book : Martindale    Page : 2133,2136   Edition : 38.  


►  Contraindication : Acute pelvic inflammatory disease, Cardiac, pulmonary, renal or hepatic disease
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 763   Edition : 3.  
  ►  Mechanism of Action :   Prostanoid receptor agonists
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 763   Edition : 3.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- MIlk thristyl with same pathway.  

  ►  Pathway with its reference as follows :-
  • Milk thristyl act as prostaglandin analogue --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )

  •   ►  URL --
  • http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA