Cefalexin is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 234   Edition : 38,

  ►   Brandname : Alexin,Betaspore,Cefmix,Cephadex,Cephaxin,Nufex,Phexin,Rofex,Sepexin,Sporidex,Ceporex,Keflex,Biolex; Cephalex; Kefalospes; Bei Dun,Cefanex,Keflex

  ►  Strength : Capsule with 250  Mg, Capsule with 500  Mg, Tablet with 1  gm, Suspension with 125/5  mg/ml, Suspension with 250/5  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 807   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, parenteral,
Reference :-   Book : Martindale    Page : 234   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Skin infections Oral 250 mg Tablet q.i.d.
2 Streptococcal pharyngitis Oral 250 mg Tablet q.i.d.
3 Uncomplicated urinary-track infection Oral 250 mg Tablet q.i.d.
4 Urinary-tract infections Oral 125 mg Tablet h.s.
5 SEVERE INFECTION Oral 50 100 mg/kg Tablet Daily in 2 divided doses.

Ref :-  Book : Martindale    Page : 234   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Susceptible bacterial infections Oral 25 50 mg/kg Tablet
2 Urinary-tract infections more than 1 Month Oral 12.5 mg/kg Tablet h.s.
3 Otitis media Oral 75 100 mg/kg Tablet
4 SEVERE INFECTION over 1 Month Oral 25 mg/kg Tablet/Capsule b.d.
5 SEVERE INFECTION 1 Month 1 Year Oral 250 mg Tablet/Capsule b.d.
6 SEVERE INFECTION 1 Year 5 Year Oral 250 mg Tablet/Capsule t.i.d.
7 SEVERE INFECTION more than 5 Year Oral 500 mg Tablet/Capsule t.i.d.

Ref :- Book : Martindale    Page : 234   Edition : 38,
►  Side Effect : hypersensitivity reactions, Skin rashes, Urticaria, eosinophilia, fever, serum-sickness, anaphylaxis, Acute intestinal nephritis, haemolytic anaemia, , Platelet dysfunction,
Ref :-   Book : Martindale    Page : 234,235   Edition : 38,

►  Drug Interaction : Drug interaction of Cefalexin is with Probenecid ,
Ref :-   Book : Martindale    Page : 234   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  The renal excretion of cefalexin, and many other cephalosporins, is delayed by probenecid.,
Ref :-   Book : Martindale    Page : 234   Edition : 38,


►  Contraindication : hypersensitive to other cephalosporins, renal impairment, penicillin-sensitive patient,
Ref :-   Book : Martindale    Page : 234,235   Edition : 38,
  ►  Mechanism of Action :   Prevents bacterial cell wall synthesis by binding to and inhibiting cell wall transpeptidases.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 806   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Neem with Another pathway, Red algae with Another pathway, Eucalyptus oil with Another pathway,

  ►  Pathway with its reference as follows :-
  • Nimbidin have Antibiotic property. --- ( Alavijeh, P. (2012). A study of antimicrobial activity of few medicinal herb . Asian Journal Of Plant Science And Research,, 2(4) )
  • Cycloeudesmol Aerropysinl have Antibiotic effect. --- (Kokate, C. (2013). Pharmacognosy. Pune: Nirali Prakashan. )
  • Antibiotic property. --- ( Duke, J. & Duke, J. (2002). Handbook of medicinal herbs. Boca Raton, FL: CRC Press )

  •   ►  URL -- http://pelagiaresearchlibrary.com/asian-journal-of-plant-science/vol2-iss4/AJPSR-2012-2-4-496-502.pdf, http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html, https://books.google.co.in/books?id=8AJkBmPDRUUC&redir_esc=y,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- CAPSCUCIN with Alter the absorbtion of capsicum.,

      ►  Reference :-
  • Williamson, E. (2009). Stockley's Herbal Medicines Interaction .. London: Pharmacutical press.

  •   ►  URL -- https://www.stonybrookmedicine.edu/sites/default/files/herbal_medicines_interactions-1.pdf,

    ►   Route of Elimination :   Biliary, Renal,
    Ref :-   Book : Martindale    Page : 234   Edition : 38,


    ►    Plasma Half-life :   Min value :-   1 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 234   Edition : 38,


    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 234   Edition : 38,