Cefixime is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 241   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Biotax-O,An Di Ke Wei; Cephoral; AB-CEF; Cefcon,Suprax,Taxim OZ,Taxim O,Maxim

  ►  Strength : Tablet with 200  mg, Tablet with 400  mg, Suspension with 100/5  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 807   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Basic & Clinical pharmacology    Page : 807   Edition : 12,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Gonorrhoea Oral 200 400 mg Tablet Aa a single dose or in two divided dose.
2 Respiratory-tract infection. Oral 200 400 mg Tablet Aa a single dose or in two divided dose.
3 Urinary-tract infections Oral 200 400 mg Tablet Aa a single dose or in two divided dose.
4 Uncomplicated gonorrhoea Oral 400 mg Tablet Aa a single dose or in two divided dose.

Ref :-  Book : Martindale    Page : 240   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Susceptible bacterial infections more than 6 Month less than 50 kg Oral 8 mg/kg Tablet

Ref :- Book : Martindale    Page : 240   Edition : 38,
Precaution :- If a Patient is using 'Cefixime' drug in  Urinary infection   disease, then Please Contraindication: severe diarrhea, hypersensitive to penicillin, .

Precaution :- If a Patient is using 'Cefixime' drug in  PID  disease, then Please Contraindication: severe diarrhea, hypersensitive to penicillin, .

Precaution :- If a Patient is using 'Cefixime' drug in  autoimmune hemolytic anemia  disease, then Please Avoid .

►  Side Effect : diarrhea, hypersenstivity, hypoprothrombinaemia, Platelet dysfunction, agranulocytosis,
Ref :-   Book : Martindale    Page : 235, 241   Edition : 38,

►  Drug Interaction : Drug interaction of Cefixime is with Anticoagulant ,  NA

  ►    Mechanism of Drug Drug Interaction :  Anticoagulants and cefixime the possibility that cefixime may increase prothrombin times.,
Ref :-   Book : Martindale    Page : 241   Edition : 38,


►  Contraindication : severe diarrhoea, hypersensitive to penicillins,
Ref :-   Book : Martindale    Page : 235,241   Edition : 37,
  ►  Mechanism of Action :   Cefixime inhibits the bacterial growth by interfearing with the transpeptidation reaction of bacterial cell wall synthesis. Cefixime is a structural analog of the natural D-Ala-D-Ala substrate, covalently bind to the active site of PBPs. This inhibits the transpeptidation reaction, halting peptidoglycan synthesis, and the cell dies. ,
Ref :-   Book : Basic & Clinical pharmacology    Page : 792   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Red algae with Another pathway, Garlic with Another pathway,

  ►  Pathway with its reference as follows :-
  • antibiotics effects --- (Kokate, C. (2013). Pharmacognosy. Pune: Nirali Prakashan. )
  • allicin and alliin have Antibiotic effect --- ( Duke, J. & Duke, J. (2002). Handbook of medicinal herbs. Boca Raton, FL: CRC Press. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html, https://books.google.co.in/books?id=8AJkBmPDRUUC&redir_esc=y,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- PROBIOTICS with Decrease in Nutrient Level, VITAMIN K with Decrease in Nutrient Level,

      ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal, Biliary,
    Ref :-   Book : Martindale    Page : 241   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   3 hours,    Max value :-   4 hours,
    Ref :-   Book : Martindale    Page : 241   Edition : 38,

    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   6 hours,
    Ref :-   Book : Martindale    Page : 241   Edition : 38,