Cefpirome Sulfate is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 247   Edition : 38  

  ►   Brandname : Bacirom, Ceforth, Cefrom, Tafrom; Luobang; Cefrom
  ►  Strength : Injection with

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 247   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV
Reference :-   Book : Martindale    Page : 247   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Susceptible infections IV 1 gm Injection b.d. Infections of the urinary tract, respiratory tract, and skin, and also septicaemia.
2 Susceptible bacterial infections IV 2 gm Injection b.d.

Ref :-  Book : Martindale    Page : 247   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1

Ref :- Book :    Page :    Edition :   
►  Side Effect : Gastrointestinal disturbance, Hypersensitivity reactions, Convulsion, Skin rashes, Urticaria, Eosinophilia, Bleeding complications, Hypoprothrombinaemia, Platelet dysfunction, Thrombophlebitis
Ref :-   Book : Martindale    Page : 235, 247   Edition : 38.   Martindale    Page : 247,235   Edition : 38.  

►  Drug Interaction : Drug interaction of Cefpirome Sulfate is with Probenecid
Ref :-   Book : Martindale    Page : 247   Edition : 38.  


  ►    Mechanism of Drug Drug Interaction :  Probenecid reduces the renal clearance of cefpirome.
Ref :-   Book : Martindale    Page : 247   Edition : 38.  


►  Contraindication : Penicillin-sensitive patient, Hypersensitive to other cephalosporins, Renal impairment
Ref :-   Book : Martindale    Page : 247,235   Edition : 38.  
  ►  Mechanism of Action :   It inhibits the bacterial growth by interfearing with the transpeptidation reaction of bacterial cell wall synthesis. Cefpirome is a structural analog of the natural D-Ala-D-Ala substrate, covalently bind to the active site of PBPs. This inhibits the transpeptidation reaction, halting peptidoglycan synthesis, and the cell dies
Ref :-   Book : Basic & Clinical pharmacology    Page : 792   Edition : 12.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Neem with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Antibacterial effect . --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL --
  • http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal
    Ref :-   Book : Martindale    Page : 247   Edition : 38.  

    ►    Plasma Half-life :   Min value :-   2 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 247   Edition : 38.  

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA