Cefpirome Sulfate is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 247   Edition : 38,

  ►   Brandname : Bacirom,Ceforth,Cefrom,Tafrom; Luobang; Cefrom

  ►  Strength : Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 247   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 247   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Susceptible infections IV 1 gm Injection b.d. Infections of the urinary tract, respiratory tract, and skin, and also septicaemia.
2 Susceptible bacterial infections IV 2 gm Injection b.d.

Ref :-  Book : Martindale    Page : 247   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : gastrointestinal disturbance, hypersensitivity reactions, convulsion, Skin rashes, Urticaria, eosinophilia, Bleeding complications, hypoprothrombinaemia, Platelet dysfunction, thrombophlebitis,
Ref :-   Book : Martindale    Page : 235, 247   Edition : 38, Martindale    Page : 247,235   Edition : 38,

►  Drug Interaction : Drug interaction of Cefpirome Sulfate is with Probenecid ,
Ref :-   Book : Martindale    Page : 247   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Probenecid reduces the renal clearance of cefpirome.,
Ref :-   Book : Martindale    Page : 247   Edition : 38,


►  Contraindication : penicillin-sensitive patient, hypersensitive to other cephalosporins, renal impairment,
Ref :-   Book : Martindale    Page : 247,235   Edition : 38,
  ►  Mechanism of Action :   It inhibits the bacterial growth by interfearing with the transpeptidation reaction of bacterial cell wall synthesis. Cefpirome is a structural analog of the natural D-Ala-D-Ala substrate, covalently bind to the active site of PBPs. This inhibits the transpeptidation reaction, halting peptidoglycan synthesis, and the cell dies,
Ref :-   Book : Basic & Clinical pharmacology    Page : 792   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Neem with Another pathway,

  ►  Pathway with its reference as follows :-
  • Antibacterial effect . --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 247   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   2 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 247   Edition : 38,

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA