Cefpodoxime Proxetil is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 248   Edition : 38      Page :   Edition :   

  ►   Brandname : Cepodem, Monocef-O, Orelox, Vantin; Banan; Apodox; Aripdox; Podomexef, Doxy
  ►  Strength : Tablet with 100 mg.  Tablet with 200 mg.  Suspension with 50/5 mg/ml.  Suspension with 100/5 mg/ml. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 807   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 248   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Respiratory- tract infections Oral 100 200 mg b.d.
2 Urinary-tract infections Oral 100 200 mg b.d.
3 Skin infections Oral 200 mg b.d.
4 Soft tissue infection Oral 200 mg b.d.
5 Uncomplicated gonorrhoea Oral 200 mg Given as a single dose.
6 Skin infections Oral 400 mg b.d.
7 Soft tissue infection Oral 400 mg b.d.

Ref :-  Book : Martindale    Page : 248   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Pharyngitis 2 Month more than 2 Month Oral 5 mg/kg b.d.
2 Acute Otitis Media Oral 400 mg o.d.
3 Pharyngitis 15 Day more than 15 Day Oral 4 mg/kg b.d.

Ref :- Book : Martindale    Page : 248   Edition : 38  
Precaution :- If a Patient is using 'Cefpodoxime Proxetil' drug in  autoimmune hemolytic anemia  disease, then Please Avoid .

►  Side Effect : Gastrointestinal disturbance, Hypersensitivity reactions, Convulsion, CNS toxicity, Skin rashes, Bleeding complications, Urticaria, Eosinophilia, Thrombophlebitis, Platelet dysfunction
Ref :-   Book : Martindale    Page : 235, 248   Edition : 38.   Martindale    Page : 248,235   Edition : 38.  

►  Drug Interaction : Drug interaction of Cefpodoxime Proxetil is with Antacid , Histamine H2-receptor antagonist,  Probenecid
Ref :-   Book : Martindale    Page : 248   Edition : 38.  


  ►    Mechanism of Drug Drug Interaction :  Absorption of cefpodoxime is decreased by antacids or histamine H2-receptor antagonists. Probenecid reduces the renal excretion of cefpodoxime.
Ref :-   Book : Martindale    Page : 248   Edition : 38.  


►  Contraindication : Penicillin-sensitive patient, Renal impairment, Hypersensitive to other cephalosporins
Ref :-   Book : Martindale    Page : 248,235   Edition : 38.  
  ►  Mechanism of Action :   Cefpodoxime inhibits the bacterial growth by interfearing with the transpeptidation reaction of bacterial cell wall synthesis. Cefpodoxime is a structural analog of the natural D-Ala-D-Ala substrate, covalently bind to the active site of PBPs. This inhibits the transpeptidation reaction, halting peptidoglycan synthesis, and the cell dies.
Ref :-   Book : Basic & Clinical pharmacology    Page : 792   Edition : 12.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Red algae with Another pathway.  

  ►  Pathway with its reference as follows :-
  • Antibiotic effect --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL --
  • http://www.vitorrentz.in/search/Text+Book+Of+Pharmacognosy .
  • +C.+K.+Kokate .
  • +A.P.+Purohit .
  • +S.B.+Gokhale .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Renal
    Ref :-   Book : Martindale    Page : 248   Edition : 38.  

    ►    Plasma Half-life :   Min value :-   2 ,    Max value :-   3 hours.  
    Ref :-   Book : Martindale    Page : 248   Edition : 38.  

    ►    Peak Plasma Concentration :   Min value :-   2,    Max value :-   3 hours.  
    Ref :-   Book : Martindale    Page : 248   Edition : 38.