Cetirizine is a Medicine belongs to antihistamines group whose information about Brand can be referenced from   Book :    Page :   Edition : , Martindale    Page : 620   Edition : 38,

  ►   Brandname : Cezor,A-Cet, Acit, Aglocet, C-Triz, CetrizineAllerTek, All Day Allergy

  ►  Strength : Tablet with 5  mg, Tablet with 10  mg, Chewable tablets with 5  mg, Chewable tablets with 10  mg, Syrup with 5  mg/5mL, Capsule with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 292   Edition : 12, Martindale    Page : 620   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 620   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Symptomatic relief of allergic conditions including rhinitis and chronic urticaria Oral 10 mg o.d. Or 5 mg twice daily.
2 Symptomatic relief of allergic conditions including rhinitis and chronic urticaria Oral 5 mg Daily in the USA.

Ref :-  Book : Martindale    Page : 619   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Allergic rhinitis and urticaria. 6 Month 23 Month Oral 2.5 mg o.d.
2 Allergic rhinitis and urticaria. 2 Year 5 Year Oral 5 mg
3 Allergic rhinitis and urticaria. 6 years and above Oral 10 mg

Ref :- Book : Martindale    Page : 619   Edition : 38,
►  Side Effect : Non-sedating antihistamines is that most have little or no antimuscarinic effect, nausea, vomiting, diarrhoea, epigastric pain, palpitations, Arrhythmias, Rashes, hypersensitivity reactions, bronchospasm, angioedema, anaphylaxis, convulsion, sweating, myalgia, paraesthesia, extrapyramidal effects, tremor, Sleep disturbances, Depression, Confusion, tinnitus, hypotension, hair loss, ,
Ref :-   Book : Martindale    Page : 619,613   Edition : 38,

►  Drug Interaction : Drug interaction of Cetirizine is with , , ,  Acenocoumarol,
Ref :-   Book : Martindale    Page : 620,1532   Edition : 38, Martindale    Page : 620,614   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  Potentially hazardous ventricular arrhythmias have occurred when the non-sedating antihistamines astemizole and terfenadine have been given with drugs liable to interfere with their hepatic metabolism, with other potentially arrhythmogenic drugs including those that prolong the QT interval, or with those likely to cause electrolyte imbalance. There has been a report, raised INR and severe epistaxis in a patient after the addition of cetirizine to long-term acenocoumarol. ,
Ref :-   Book : Martindale    Page : 620,614,1532   Edition : 38,


►  Contraindication : hepatic impairment, renal impairment,
Ref :-   Book : Martindale    Page : 619   Edition : 38,
  ►  Mechanism of Action :   Competitive antagonism/inverse agonism at H1 receptor.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 291   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 620   Edition : 38,


►    Plasma Half-life :
  Min value :-   10 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 620   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   within about an hour,    Max value :-   NA
Ref :-   Book : Martindale    Page : 620   Edition : 38,