Chenodeoxycholic acid is a Medicine belongs to Gallstones dissolving drug group whose information about Brand can be referenced from   Book : Martindale    Page : 2475   Edition : 38  

  ►   Brandname : Chenodal; Chenofalk
  ►  Strength : Tablet with

Reference of this Medicine for its Strength can be taken from   Book :    Page :    Edition :   
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 2475   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Gallstones Oral 15 mg/kg Daily.

Ref :-  Book : Martindale    Page : 2475   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Classic Refsum disease Oral 100 250 mg o.d.

Ref :- Book : Nelson's textbook of Pediatrics    Page : 467   Edition : 19  
►  Side Effect : Nausea, Vomiting, Gastrointestinal disturbance, Diarrhea, Hypercholesterolaemia
Ref :-   Book : Martindale    Page : 2475, 2639   Edition : 38.  

►  Drug Interaction : Drug interaction of Chenodeoxycholic acid is with Antacid , , ,  Clofibrate, Cholestyramine
Ref :-   Book : Martindale    Page : 2639   Edition : 38.   Martindale    Page : 2475,2639   Edition : 38.  


  ►    Mechanism of Drug Drug Interaction :  It should not be used with drugs that increase bile cholesterol such as oestrogenic hormones and cholesterol- lowering drugs such as clofibrate. Use with bile-acid binding drugs including antacids, charcoal, and colestyramine should be avoided since this may reduce the effectiveness of therapy with Chenodeoxycholic acid.
Ref :-   Book : Martindale    Page : 2475,2639   Edition : 38.  


►  Contraindication : Hepatic disorder, Intestinal disorder, Pregnancy
Ref :-   Book : Martindale    Page : 2475,2639   Edition : 38.  
  ►  Mechanism of Action :   Chenodeoxycholic acid is a naturally occurring bile acid. When given orally it reduces hepatic synthesis of cholesterol and provides additional bile salts to the pool available for solubilisation of cholesterol and lipids.
Ref :-   Book : Martindale    Page : 2475   Edition : 38.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Artichoke i.e Cynara scolymus with Another pathway.  

  ►  Pathway with its reference as follows :-
  • cynarin stimulate flow of bile into the intestine.i --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )

  •   ►  URL --
  • http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Fecal, Hepatic (Metabolism)
    Ref :-   Book : Martindale    Page : 2475   Edition : 38.  

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA