Chenodeoxycholic acid is a Medicine belongs to Gallstones dissolving drug group whose information about Brand can be referenced from   Book : Martindale    Page : 2475   Edition : 38,

  ►   Brandname : Chenodal; Chenofalk

  ►  Strength : Tablet with   ,

Reference of this Medicine for its Strength can be taken from   Book :    Page :    Edition : ,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 2475   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Gallstones Oral 15 mg/kg Daily.

Ref :-  Book : Martindale    Page : 2475   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Classic Refsum disease Oral 100 250 mg o.d.

Ref :- Book : Nelson's textbook of Pediatrics    Page : 467   Edition : 19,
►  Side Effect : nausea, vomiting, gastrointestinal disturbance, diarrhea, hypercholesterolaemia,
Ref :-   Book : Martindale    Page : 2475, 2639   Edition : 38,

►  Drug Interaction : Drug interaction of Chenodeoxycholic acid is with Antacid , , ,  Clofibrate, Cholestyramine ,
Ref :-   Book : Martindale    Page : 2639   Edition : 38, Martindale    Page : 2475,2639   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  It should not be used with drugs that increase bile cholesterol such as oestrogenic hormones and cholesterol- lowering drugs such as clofibrate. Use with bile-acid binding drugs including antacids, charcoal, and colestyramine should be avoided since this may reduce the effectiveness of therapy with Chenodeoxycholic acid.,
Ref :-   Book : Martindale    Page : 2475,2639   Edition : 38,


►  Contraindication : hepatic disorder, intestinal disorder, Pregnancy,
Ref :-   Book : Martindale    Page : 2475,2639   Edition : 38,
  ►  Mechanism of Action :   Chenodeoxycholic acid is a naturally occurring bile acid. When given orally it reduces hepatic synthesis of cholesterol and provides additional bile salts to the pool available for solubilisation of cholesterol and lipids.,
Ref :-   Book : Martindale    Page : 2475   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Artichoke i.e Cynara scolymus with Another pathway,

  ►  Pathway with its reference as follows :-
  • cynarin stimulate flow of bile into the intestine.i --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Fecal, Hepatic (Metabolism),
    Ref :-   Book : Martindale    Page : 2475   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA