Chlorzoxazone is a Medicine belongs to muscle relaxant (Spasmolytic) group whose information about Brand can be referenced from   Book : Martindale    Page : 2059   Edition : 37,

  ►   Brandname : New panazox,Parafon forte DSC,Paraflex

  ►  Strength : Tablet with 500  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 2059   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Severe muscle spasms Oral 500 mg Tablet t.i.d/q.i.d
2 Symptomatic treatment of painful muscle spasm associated with musculoskeletal conditions Oral 250 mg Tablet t.i.d/q.i.d

Ref :-  Book : Martindale    Page : 2059   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : drowsiness, Dizziness, headache, gastrointestinal bleeding,
Ref :-   Book : Martindale    Page : 2058   Edition : 37,

►  Drug Interaction : Drug interaction of Chlorzoxazone is with Alcohol, CNS depressant,  NA

  ►    Mechanism of Drug Drug Interaction :  The CNS effects of chlorzoxazone may be enhanced by alcohol and other CNS depressants. ,
Ref :-   Book : Martindale    Page : 2058   Edition : 37,


►  Contraindication : hepatic impairment, liver toxicity,
Ref :-   Book : Martindale    Page : 2058   Edition : 37,
  ►  Mechanism of Action :   Chlorzoxazone is a centrally acting skeletal muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain.,
Ref :-   Book : Martindale    Page : 2059   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Poppy seed with same pathwaysame pathway, Poppy seed with same pathwaysame pathway,

  ►  Pathway with its reference as follows :-
  • muscle relaxant effect . --- ( Madani, S., T, S., & I.J, K. (2014). A REVIEW ON PAPAVER SOMNIFERUM (OPIUM POPPY). International Journal Of Universal Pharmacy And Bio Sciences, 3(6), 377-393. )
  • muscle relaxant effect . --- ( Madani, S., T, S., & I.J, K. (2014). A REVIEW ON PAPAVER SOMNIFERUM (OPIUM POPPY). International Journal Of Universal Pharmacy And Bio Sciences, 3(6), 377-393. )
  • muscle relaxant effect . --- ( Madani, S., T, S., & I.J, K. (2014). A REVIEW ON PAPAVER SOMNIFERUM (OPIUM POPPY). International Journal Of Universal Pharmacy And Bio Sciences, 3(6), 377-393. )
  • muscle relaxant effect . --- ( Madani, S., T, S., & I.J, K. (2014). A REVIEW ON PAPAVER SOMNIFERUM (OPIUM POPPY). International Journal Of Universal Pharmacy And Bio Sciences, 3(6), 377-393. )

  •   ►  URL -- http://www.ijupbs.com/Uploads/30.%20RPA1415147015.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- WATERCRESS with Dietary Substance is Drug Enhancer, THIAMINE with Dietary Substance is Drug Enhancer, ST JOHNS WORT with Dietary Substance is Drug Enhancer,

      ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press.
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart
  • Driver, S. (2009). Stockleys Herbal Medicines Interactions. Royal pharmaceutical Society of Great Britain: Pharmaceutical press.

  •   ►  URL -- http://www.otto-wipfel.co.uk/otto/supplements-medication/DRUG-HERB-VITAMINS-INTERACTIONS-A-Z_Guide.pdf , http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf, https://www.stonybrookmedicine.edu/sites/default/files/herbal_medicines_interactions-1.pdf,


    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- with May cause excessive drawsinesss when taken with muscle relaxcent ., VALERIAN with Valerian cause sedative effect with chlorzoxazone .,

      ►  Reference :-
  • Eldelberg, D. The New Age of nutritional and herbal remedies. New Zealand.
  • Driver, S. (2009). Stockleys Herbal Medicines Interactions. Royal pharmaceutical Society of Great Britain: Pharmaceutical press

  •   ►  URL -- https://books.google.co.in/books?id=WZhj8EO9N3sC&pg=PA49&lpg=PA49&dq=The+New+Age+of+nutritional+and+herbal+remedies.++book&source=bl&ots=UVld-vNZL0&sig=5KwkKUUvW45p0TkfVUCtMZxnbow&hl=en&sa=X&ved=0ahUKEwiajLCNocrOAhVMto8KHfD2D-4Q6AEIMDAE#v=onepage&q=The%20, https://www.stonybrookmedicine.edu/sites/default/files/herbal_medicines_interactions-1.pdf,

    ►   Route of Elimination :   Renal,
    Ref :-   Book : Martindale    Page : 2059   Edition : 37,


    ►    Plasma Half-life :   Min value :-   1 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 2059   Edition : 37,


    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   2 hours,
    Ref :-   Book : Martindale    Page : 2059   Edition : 37,