Cilnidipine is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1337   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Jiuyue; Cilacar,Nulong

  ►  Strength :

A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1337   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 hypertension Oral 5 10 mg o.d.

Ref :-  Book : Martindale    Page : 1337   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Dizziness, flushing, headache, hypotension, peripheral oedema, tachycardia, palpitations, nausea, gastrointestinal disturbance, increased micturition frequency, lethargy, eye pain, visual disturbances, mental depression,
Ref :-   Book : Martindale    Page : 1482   Edition : 37,

►  Drug Interaction : Drug interaction of Cilnidipine is with Aldesleukin , Quinidine , Carbamazapine , Phenytoin , Rifampicin , Cimetidine , Erythromycin , Pioglitazone Hydrochloride ,
Ref :-   Book : Martindale    Page : 958   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Nifedipine is extensively metabolised in the liver by the cytochrome P450 isoenzyme CYP3A4, and interactions may occur with other drugs, such as quinidine, sharing the same metabolic pathway, and with enzyme inducers, such as carbamazepine, phenytoin, and rifampicin, and enzyme inhibitors, such as cimetidine, erythromycin, and HIVprotease inhibitors. ,
Ref :-   Book : Martindale    Page : 1485   Edition : 37,


►  Contraindication : NA
  ►  Mechanism of Action :   Cilnidipine is a dihydropyridine calcium-channel blocker Dihydropyridine calcium-channel blockers act on slow, L-type channels. They have a greater selectivity for vascular smooth muscle than for myocardium and therefore their main effect is vasodilatation. They are non-rate-limiting, with little or no action at the SA or AV nodes, and negative inotropic activity is rarely seen at therapeutic doses.,
Ref :-   Book : Martindale    Page : 1244,1337   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Ginger (Zingiber officinale) with same pathway,

  ►  Pathway with its reference as follows :-
  • calcium channel blocker . --- (Ghayur, Muhammad Nabeel and Anwarul Hassan Gilani. "Ginger Lowers Blood Pressure Through Blockade Of Voltage-Dependent Calcium Channels". Journal of Cardiovascular Pharmacology 45.1 (2005): 74-80. Web. )

  •   ►  URL -- https://www.ncbi.nlm.nih.gov/pubmed/15613983,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA