Cisatracurium is a Medicine belongs to Neuromuscular blocker group whose information about Brand can be referenced from   Book : Martindale    Page : 2034   Edition : 38,

  ►   Brandname : Nimbex; Acris; Artacil; Atcurium

  ►  Strength : Injection with 2  mg/ml, Injection with 10  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 481   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 2030   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Muscle relaxant IV 150 micrograms/kg Injection

Ref :-  Book : Martindale    Page : 2030   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Muscle relaxant More than 1Month IV 150 micrograms/kg Injection

Ref :- Book : Martindale    Page : 2030   Edition : 38,
►  Side Effect : tachycardia, rise in blood pressure, bronchospasm,
Ref :-   Book : Martindale    Page : 2030   Edition : 38,

►  Drug Interaction : Drug interaction of Cisatracurium is with Anticholinesterase,  NA

  ►    Mechanism of Drug Drug Interaction :  A number of drugs may influence neuromuscular transmission and thus interfere with the action of both competitive and depolarising neuromuscular blockers, resulting in potentiation or antagonism of neuromuscular block. Some interactions may be advantageous, such as the reversal of competitive neuromuscular block by anticholinesterases.,
Ref :-   Book : Martindale    Page : 2031   Edition : 38,


►  Contraindication : asthma, Hypersensitivity to any neuromuscular blockers, renal impairment,
Ref :-   Book : Martindale    Page : 2030   Edition : 38,
  ►  Mechanism of Action :   Competitive neuromuscular blockers act by competing with acetylcholine for receptors on the motor end-plate of the neuromuscular junction to produce blockade. The muscles that produce fine rapid movements such as those of the face are the first to be affected, followed by those of the limbs and torso; the last to be affected are those of the diaphragm.,
Ref :-   Book : Martindale    Page : 2030   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Kava with Another pathway,

  ►  Pathway with its reference as follows :-
  • muscle relaxant effect . --- (Cairney, S., Clough, A., Maruff, P., Collie, A., Currie, B., & Currie, J. (2003). Saccade and Cognitive Function in Chronic Kava Users. Neuropsychopharmacology, 28(2), 389-396. doi:10.1038/sj.npp.1300052 )

  •   ►  URL -- http://www.nature.com/npp/journal/v28/n2/full/1300052a.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Renal,
    Ref :-   Book : Martindale    Page : 2033   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   22 minutes,    Max value :-   29 minutes,
    Ref :-   Book : Martindale    Page : 2033   Edition : 38,

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA