Clopidogrel is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1344   Edition : 38,    Page :   Edition : ,

  ►   Brandname : Cloflow,Clopact,Plavix,Aclotil; Adplatt,Deplatt,Ecosprin gold,Clopivas AP,Deplatt A

  ►  Strength : Tablet with 75  mg, Tablet with 300  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 617   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1343   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Prophylaxis of thromboembolism Oral 75 mg Tablet o.d.
2 Acute ST-elevation myocardial infarction Oral 75 mg Tablet o.d.
3 Non-Q wave myocardial infarction Oral 300 mg Tablet o.d. Followed by 75 mg once daily.
4 unstable angina Oral 300 mg Tablet o.d. Followed by 75 mg once daily.

Ref :-  Book : Martindale    Page : 1343   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Congenital heart disease 6 Week 16 Year Oral 1 3 mg/kg Tablet o.d.
2 Arterial ischaemic stroke 1.5 Year 17 Year Oral 0.5 2.4 mg/kg Tablet
3 Antiplatelet activity 0 Month 24 Month Oral 200 micrograms/kg Tablet

Ref :- Book : Martindale    Page : 1343   Edition : 38,
►  Side Effect : gastrointestinal disturbance, Skin rashes, neutropenia, thrombotic thrombocytopenic purpura, aplastic anaemia, bleeding, ,
Ref :-   Book : Martindale    Page : 1343,1512   Edition : 38, Martindale    Page : 1343   Edition : 38,

►  Drug Interaction : Drug interaction of Clopidogrel is with Anticoagulant , Antiplatelet drugs, NSAIDS, ,  NA

  ►    Mechanism of Drug Drug Interaction :  Clopidogrel should be used with caution in patients receiving other drugs that increase the risk of bleeding, including anticoagulants, other antiplatelets, and NSAIDs. Drugs that inhibit the cytochrome P450 isoenzyme involved in the metabolism of clopidogrel may reduce its antiplatelet effect. Clopidogrel may inhibit the isoenzyme CYP2C9 and interactions with drugs metabolised by this isoenzyme are theoretically possible it may also inhibit CYP2B6. ,
Ref :-   Book : Martindale    Page : 1344   Edition : 38,


►  Contraindication : stopping clopidogrel 5 to 7 days before elective surgery., drugs that increase the risk of bleeding, including anticoagulants, other antiplatelets, and NSAIDs.,
Ref :-   Book : Martindale    Page : 1343   Edition : 38,
  ►  Mechanism of Action :   It is an analogue of ticlopidine and acts by inhibiting adenosine diphosphate- mediated platelet aggregation,
Ref :-   Book : Martindale    Page : 1343   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Garlic with Another pathway,

  ►  Pathway with its reference as follows :-
  • Cardioprotective effect . --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Hepatic (Metabolism), Renal,
    Ref :-   Book : Martindale    Page : 1344   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA