Clotrimazole is a Medicine belongs to Antifungal group whose information about Brand can be referenced from   Book : Martindale    Page : 576   Edition : 38,

  ►   Brandname : Antican,Calcrem,Canazole,Lotrimin-AF,Mycelex; Candasia; Combi; Canesten

  ►  Strength : Cream with 1  %, Vaginal Tablets with 100  mg, Vaginal Tablets with 200  mg, Vaginal Tablets with 500  mg, Lotion with 1  %, Powder with 1  %, Aerosol with 1  %, Solution with 1  %, Vaginal cream with 1  %, Vaginal cream with 2  %, Troches with 10  mg,

Reference of this Medicine for its Strength can be taken from   Book : Goodman    Page : 1587   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical, Oral,
Reference :-   Book : Martindale    Page : 576   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Fungal infections Topical 1 % Cream b.d/t.i.d Lotion, spray or solution for 2 to 4 weeks.
2 Vulvovaginal candidiasis Vaginal 100 mg Pessary Dose: For 6 days,
3 Oropharyngeal candidiasis Oral 10 mg Lozenge Dose: Five times daily for 14 days.
4 Fungal otitis externa Topical 1 % Solution
5 Vulvovaginal candidiasis Vaginal 200 mg Pessary For 3 days.
6 Vulvovaginal candidiasis Vaginal 500 mg Pessary A single dose.
7 Vulvovaginal candidiasis Vaginal 1 % Vaginal cream Also available 2 or 10% vaginal cream.

Ref :-  Book : Martindale    Page : 576   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : nausea, vomiting, unpleasant mouth sensations, pruritus, Irritation, burning sensation, contact allergic dermatitis, damage latex contraceptives, gastrointestinal disturbance, dysuria, mental depression, elevation of liver enzymes,
Ref :-   Book : Martindale    Page : 576   Edition : 38,

►  Drug Interaction : Drug interaction of Clotrimazole is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Pregnancy,
Ref :-   Book : Martindale    Page : 576   Edition : 38,
  ►  Mechanism of Action :   Reduces ergosterol synthesis by inhibition of fungal cytochrome P450 enzymes.,
Ref :-   Book : Basic & Clinical pharmacology    Page : 853   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Tea tree oil with Another pathway, Angeer with Another pathway,

  ►  Pathway with its reference as follows :-
  • Anti-fungal --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )
  • 6-o-acyl-beta-d-glucosyl-beta-sitosterols.found in fig or anjeer have anticancer property. --- (Joseph, Baby. "Pharmacognostic And Phytochemical Properties Of Ficus Carica Linn –An Overview". International Journal of PharmTech Research 3.1 (2017): 08-12,. Print. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html, http://sphinxsai.com/Vol.3No.1/pharm_jan-mar11/pdf/JM11(%20PT=03)%2008-12.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal, Hepatic (Metabolism),
    Ref :-   Book : Martindale    Page : 576   Edition : 38,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA