Colestipol is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1346   Edition : 38  

  ►   Brandname : Colestid
  ►  Strength : Tablet with 1 gm.  Packets granules with 5 gm.  Suspension with

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 633   Edition : 12   Martindale    Page : 1346   Edition : 38  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Basic & Clinical pharmacology    Page : 633   Edition : 12  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Hyperlipidaemia Oral 5 gm Suspension b.d.
2 Hyperlipidaemia Oral 2 16 gm Tablet Daily.
3 Hyperlipidemia Oral 5 gm Suspension Daily.

Ref :-  Book : Martindale    Page : 1345   Edition : 38  



Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Hyperlipidaemia less than 8 Year Oral 5 40 gm

Ref :- Book : Nelson's textbook of Pediatrics    Page : 481   Edition : 19  
►  Side Effect : Bloating, Dyspepsia, Flatulence, Bleeding diathesis, Increase in triglycerides levels
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 330   Edition : 3.  

►  Drug Interaction : Drug interaction of Colestipol is with Thiazide Diuretics , Statins,  Furosemide , Propranolol , Warfarin
Ref :-   Book : Goodman    Page : 899   Edition : 12.  


  ►    Mechanism of Drug Drug Interaction :  colestipol bind and interfere with the absorption of many drugs, including some thiazides, furosemide, propranolol, digoxin, warfarin, and some of the statins.
Ref :-   Book : Goodman    Page : 899   Edition : 12.  


►  Contraindication : Biliary obstruction
Ref :-   Book : Martindale    Page : 1345,1347   Edition : 38.  
  ►  Mechanism of Action :   Bind to bile acids, preventing enterohepatic circulation→LDL decreases up to 28%, HDl increases ̴5% .
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 330   Edition : 3.  

Pathway of DIETARY Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Garlic with Another pathway.  

  ►  Pathway with its reference as follows :-
  • lower blood cholesterol . --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )

  •   ►  URL --
  • http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf .

  • DIETARY Substance Interactions


    ​   ► This Medicine interact with :- VITAMIN A with Decrease in Nutrient Level.   VITAMIN D with Decrease in Nutrient Level.   VITAMIN E with Decrease in Nutrient Level.   VITAMIN K with Decrease in Nutrient Level.   BETACAROTENE with Decrease in Nutrient Level.  

      ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf
    http://www.otto-wipfel.co.uk/otto/supplements-medication/DRUG-HERB-VITAMINS-INTERACTIONS-A-Z_Guide.pdf


    ContraIndication DIETARY Substance


    ​   ► This Medicine contraindicate with :- VITAMIN A with Lower plasma level of vit A..   VITAMIN E with Lower plasma level of vit E..  

      ►  Reference :-
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart
  • Michael, Z. (2007). Hand book of nutrition. New York: Thieme Stuttgart

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf

    ►   Route of Elimination :   NA

    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA