Cyclopentolate is a Medicine belongs to anticholinergic group whose information about Brand can be referenced from   Book : Martindale    Page : 2006   Edition : 38,

  ►   Brandname : Cyclate,Cyclogik,Mydrilate,Cyclogyl

  ►  Strength : Ophthalmic Solution with 0.5  %, Ophthalmic Solution with 1  %, Ophthalmic Solution with 2  %, Eye Drop with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 127   Edition : 12, Martindale    Page : 2006   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Topical,
Reference :-   Book : Martindale    Page : 2006   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Uveitis Topical Ophthalmic Solution q.i.d. 0.5%.
2 Iritis Topical Ophthalmic Solution q.i.d. 0.5%.

Ref :-  Book : Martindale    Page : 2006   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Uveitis Topical Ophthalmic Solution

Ref :- Book : Martindale    Page : 2006   Edition : 38,
►  Side Effect : raised intra-ocular pressure, Blurred Vision, mydriasis, cycloplegia, temporary irritation in eye, photophobia, Dryness of the mouth, reduced bronchial secretions, Flushing of the skin, dryness of the skin, arrhythmia, difficulty in micturition, constipation, constipation, transient bradycardia followed by tachycardia,
Ref :-   Book : Martindale    Page : 2006, 1312   Edition : 38,

►  Drug Interaction : Drug interaction of Cyclopentolate is with antihistamines, Phenothiazine, Tricyclic antidepressant , Monoamine Oxidase Inhibitor,  Amantadine , Cisapride , Domperidone , Metoclopramide ,
Ref :-   Book : Martindale    Page : 2006, 1312   Edition : 38,


  ►    Mechanism of Drug Drug Interaction :  The effects of Cyclopentolate and other antimuscarinics may be enhanced by use with other drugs having antimuscarinic properties, such as amantadine, some antihistamines, phenothiazine antipsychotics, and tricyclic antidepressants. Inhibition of drug-metabolising enzymes by MAOIs may possibly enhance the effects of Cyclopentolate. The reduction in gastric motility caused by Cyclopentolate may affect the absorption of other drugs. Cyclopentolate may also antagonise the gastrointestinal effects of cisapride, domperidone, and metoclopramide. Antimuscarinics and parasympathomimetics may counteract each others effects. ,
Ref :-   Book : Martindale    Page : 2006,1312   Edition : 38,


►  Contraindication : prostatic hyperplasia, Myasthenia gravis, angle -closure glucoma, tachycardia, thyrotoxicosis, heart failure, cardiac surgery,
Ref :-   Book : Martindale    Page : 2006, 1312   Edition : 38,
  ►  Mechanism of Action :   Cyclopentolate hydrochloride is a tertiary amine antimuscarinic.,
Ref :-   Book : Martindale    Page : 2006   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- VITAMIN A with Interfere with the activation of drug ., VITAMIN E with Interfere with the activation of drug ., BETACAROTENE with Interfere with the activation of drug ., GLUTAMINE with It has successfully reduced chemotherapy induced mouth sores ., MELATONIN with It reduce their side effect or improving drug efficacy ., SELENIUM with Selenium had a smaller reduction in white blood cell count and fewer chemotherapy side effects such as nausea , hair loss , weakness , and loss of appetite ., GINGER (ZINGIBER OFFICINALE) with Ginger can be helpful in alleviating nausea and vomiting caused by chemotherapy .,

  ►  Reference :-
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press
  • Gaby, A. (2006). A–Z Guide to Drug-Herb-Vitamin Interactions. 2nd ed. New York: Three Rivers Press

  •   ►  URL -- http://www.lifestyle-clinic.net/wp-content/uploads/2013/07/A-Z_Guide.pdf,

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA