Daunomycin is a Medicine belongs to group whose information about Brand can be referenced from   Book : Martindale    Page : 776   Edition : 37,

  ►   Brandname : Daunotic,Norubin,Cerubidine

  ►  Strength : Injection with 20  mg, Injection with 50  mg,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 776   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 776   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Kaposi’s sarcoma IV 40 mg/m2 Injection bis in 7 d.
2 Acute lymphoblastic leukaemia IV infusion 45 mg/m2 Injection
3 Myeloid leukaemias IV infusion 45 mg/m2 Injection

Ref :-  Book : Martindale    Page : 776   Edition : 37, Martindale    Page : 777   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Acute lymphoblastic leukaemia IV 25 mg/m2 Injection QWK
2 IV 1 mg/kg Injection

Ref :- Book : Martindale    Page : 776   Edition : 37,
►  Side Effect : Cardiotoxicity, local tissue necrosis, acute syndrome of back pain, flushing, chest tightness,
Ref :-   Book : Martindale    Page : 776   Edition : 37,

►  Drug Interaction : Drug interaction of Daunomycin is with NA

  ►    Mechanism of Drug Drug Interaction :  Doxorubicin is reported to inhibit the intracellular activation of stavudine and hence its antiviral effect,
Ref :-   Book : Martindale    Page : 776   Edition : 37,


►  Contraindication : NA
  ►  Mechanism of Action :   It is thought to have multiple modes of action including intercalation of DNA leading to an inhibition of DNA and RNA synthesis, inhibition of topoisomerase II, free radical formation, and alterations in cell membranes,
Ref :-   Book : Martindale    Page : 776   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 776   Edition : 37,


►    Plasma Half-life :
  Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,