Deferiprone is a Medicine belongs to Chelators Antidotes and Antagonists group whose information about Brand can be referenced from   Book : Martindale    Page : 1544   Edition : 38,

  ►   Brandname : Kelfer,Ferriprox

  ►  Strength : Tablet with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1543   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1543   Edition : 38,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Iron overload in patients with thalassaemia Oral 25 mg/kg Tablet t.i.d.

Ref :-  Book : Martindale    Page : 1543,1544   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Iron overload in patients with thalassaemia Oral 25 mg/kg Tablet t.i.d.

Ref :- Book : Martindale    Page : 1543,1544   Edition : 38,
►  Side Effect : neutropenia, agranulocytosis, thrombocytopenia, gastrointestinal disorders, diarrhea, nausea, vomiting, abdominal pain, headache, asthenia, peripheral edema, Dizziness, Somnolence, pruritus, Urticaria, reddish-brown discoloration of the urine, increase or decrease in appetite, musculoskeletal pain, Arthropathy, Reduces plasma-zinc concentrations,
Ref :-   Book : Martindale    Page : 1543   Edition : 38,

►  Drug Interaction : Drug interaction of Deferiprone is with drugs that may cause neutropenia or agranulocytosis, Antacid ,  NA

  ►    Mechanism of Drug Drug Interaction :  Deferiprone chelates trivalent metal ions and could interact with aluminium-containing preparations; it should not be given with aluminium-containing antacids. Due to the risk of additive toxicity, use with drugs that may cause neutropenia or agranulocytosis is not recommended. ,
Ref :-   Book : Martindale    Page : 1543,1544   Edition : 38,


►  Contraindication : renal impairment, hepatic impairment,
Ref :-   Book : Martindale    Page : 1543   Edition : 38,
  ►  Mechanism of Action :   Deferiprone is an orally active iron chelator,
Ref :-   Book : Martindale    Page : 1543   Edition : 38,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 1544   Edition : 38,


►    Plasma Half-life :
  Min value :-   45 minutes,    Max value :-   60 minutes,
Ref :-   Book : Martindale    Page : 1544   Edition : 38,

►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   3 hours,
Ref :-   Book : Martindale    Page : 1544   Edition : 38,