Diphtheria, Tetanus, Pertussis, Poliomyelitis, and Haemophilus Influenzae Vaccines is a Medicine belongs to vaccine group whose information about Brand can be referenced from   Book : Martindale    Page : 2418   Edition : 37,

  ►   Brandname : Infanrix IPV + Hib,Pediacel,Pentacel,Pentavac

  ►  Strength : Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 2418   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IM,
Reference :-   Book : Martindale    Page : 2418   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info

Ref :-  Book :




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 IM 0.5 mL Injection

Ref :- Book : Martindale    Page : 2418   Edition : 37,
►  Side Effect : inflammation, lymphangitis, fever, headache, malaise, hypersensitivity reactions, anaphylaxis,
Ref :-   Book : Martindale    Page : 2406, 2417   Edition : 37,

►  Drug Interaction : Drug interaction of Diphtheria, Tetanus, Pertussis, Poliomyelitis, and Haemophilus Influenzae Vaccines is with Antineoplastic , Corticosteroid ,  NA

  ►    Mechanism of Drug Drug Interaction :  Vaccines to induce an immune response can be influenced by the recent use of other vaccines or immunoglobulins. Patients receiving immunosuppressant therapy, including antineoplastics or therapeutic doses of corticosteroids, may also display a reduced response to vaccines,
Ref :-   Book : Martindale    Page : 2407, 2418   Edition : 37,


►  Contraindication : , anaphylactic reaction, Some vaccines are prepared in egg cultures and are contra-indicated in persons with a confirmed anaphylactic reaction to egg, If any alcohol or disinfectant is used for cleansing the skin it should be allowed to evaporate before vaccination otherwise inactivation of live vaccines may occur, HIV positive patients with immunosuppression,
Ref :-   Book :    Page :    Edition : , Martindale    Page : 2407, 2417   Edition : 37,
  ►  Mechanism of Action :   Prompt antibody response follows and high concentrations of IgG occur in the blood (the secondary response).,
Ref :-   Book : Martindale    Page : 2407, 2417   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- GINSING with Ginseng extracts may increase antibody response and effectiveness of vaccine by enhancing antigen -presenting cell ( APC) activity . So it should be given before vaccination .,

  ►  Reference :-
  • Stargrove, Mitchell Bebel, Jonathan Treasure, and Dwight L McKee. Herb, Nutrient, And Drug Interactions. 1st ed. St. Louis, Mo.: Mosby Elsevier, 2008. Print.

  •   ►  URL -- https://books.google.co.in/books?id=49kLK--eumEC&printsec=frontcover&dq=Herb, +nutrient, +and+drug+interactions&hl=en&sa=X&redir_esc=y#v=onepage&q=Herb%2C%20nutrient%2C%20and%20drug%20interactions&f=false,

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :   Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA