Docosahexaenoic acid/Eicosapentaenoic acid is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1497   Edition : 37,    Page :   Edition : ,

  ►   Brandname : Maxepa, Omacor, Pure Omega, Cardi-Omega 3, Cholestin,Gembone

  ►  Strength : Capsules with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1497   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1497   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Hypertriglyceridaemia Oral 5 gm Capsule b.d. Preparation containing 17% eicosapentaenoic acid and 11.5% docosahexaenoic acid, or 2 to 4 g daily of a preparation containing 46% eicosapentaenoic acid and 38% docosahexaenoic acid
2 Secondary prevention of myocardial infarction Oral 1 gm Capsule Given daily of a preparation containing 46% eicosapentaenoic acid and 38% docosahexaenoic acid may be given.

Ref :-  Book : Martindale    Page : 1497   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : Gastrointestinal disturbances, nausea, eructation, vomiting, Abdominal distension, diarrhoea, constipation, Moderate increases in hepatic transaminases have been reported in patients with hypertriglyceridaemia, ,
Ref :-   Book : Martindale    Page : 1496   Edition : 37,

►  Drug Interaction : Drug interaction of Docosahexaenoic acid/Eicosapentaenoic acid is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : hepatic impairment, Omega-3 fatty acids have antithrombotic activity and should be given with caution to patients with haemorrhagic disorders or to those receiving anticoagulants or other drugs affecting coagulation, Caution may also be required in asthmatic patients sensitive to aspirin since omega-3 fatty acids may affect prostaglandin synthesis,
Ref :-   Book : Martindale    Page : 1496   Edition : 37,
  ►  Mechanism of Action :   The main dietary omega-3 fatty acids are eicosapentaenoic acid and docosahexaenoic acid and are derived from marine fish. Omega-3 fatty acids are long-chain polyunsaturated fatty acids containing 18 to 22 carbon atoms and a varying number of double bonds, the first of which is in the n-3 position. They are essential fatty acids and must be obtained from the diet. They have an important role as eicosanoid precursors and as components of cell membranes; in humans, they compete with arachidonic acid, an omega-6 fatty acid precursor. Their actions in humans include a hypolipidaemic action (especially a reduction in plasma triglycerides), an anti-inflammatory action, and an antiplatelet effect.,
Ref :-   Book : Martindale    Page : 1496   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   NA


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA