Dopamine is a Medicine belongs to sympathomimetic group whose information about Brand can be referenced from   Book : Martindale    Page : 1402   Edition : 37,

  ►   Brandname : Dopinga

  ►  Strength : Injection with 40  mg/ml, Injection with 80  mg/ml, Injection with 160  mg/ml, Injection with 80/100  mg/ml, Injection with 160/100  mg/ml, Injection with 320/100  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 148   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV infusion,
Reference :-   Book : Martindale    Page : 1402   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Cardiovascular disorders IV infusion 1 5 micrograms/kg/min Injection Dose: gradually increased by up to 5 to 10 micrograms/kg per minute according to the patient’s blood pressure, cardiac output, and urine output

Ref :-  Book : Martindale    Page : 1402   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Cardiovascular disorders IV infusion 3 micrograms/kg/min Injection
2 Cardiovascular disorders 1 month IV infusion 5 micrograms/kg/min Injection

Ref :- Book : Martindale    Page : 1402   Edition : 37,
►  Side Effect : anxiety, fear, Restlessness, insomnia, Confusion, irritability, headache, dyspnoea, weakness, anorexia, nausea, vomiting, palpitations, tachycardia, arrhythmia, mydriasis, difficulty in micturition, urinary retention, piloerection, sweating, increased salivation, Hypoprolactinemia, angina, cardiac arrest,
Ref :-   Book : Martindale    Page : 1401,1544   Edition : 37,

►  Drug Interaction : Drug interaction of Dopamine is with , Tricyclic antidepressant , Monoamine Oxidase Inhibitors, Cardiac Glycosides, Antiarrhythmics,  Halothane , Guanethidine, dexamfetamine, Dopexamine, Ephedrine , Isometheptene, Mephentermine, Methylphenidate , Phentermine, Phenylephrine , Phenylpropanolamine, Pseudoephedrine,
Ref :-   Book : Martindale    Page : 1401,1545   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Increased cardiac effects may occur with drugs that increase the sensitivity of the myocardium to beta1 agonists; hazardous arrhythmias may occur with volatile anaesthetics, particularly cyclopropane or halothane. Direct-acting sympathomimetics with alphaagonist actions specifically reverse the hypotensive effect of adrenergic neurone blockers such as guanethidine, and severe hypertension may result. Sympathomimetics for which the risk is particularly high include dexamfetamine, dopamine, dopexamine, ephedrine, isometheptene, mephentermine, metaraminol, methylphenidate, phentermine, phenylephrine, phenylpropanolamine, and pseudoephedrine. Tricyclic antidepressants block the inactivation of adrenaline and noradrenaline by uptake into the nerve endings and may increase their effect; hypertension and arrhythmias may occur. Dopamine has both direct and indirect actions and may therefore interact with MAOIs; the dose of dopamine should be substantially reduced in patients taking MAOIs. ,
Ref :-   Book : Martindale    Page : 1401,1545   Edition : 37,


►  Contraindication : Ventricular fibrillation, uncorrected tachyarrhythemias, phaeochromocytoma,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 435   Edition : 3,
  ►  Mechanism of Action :   Increase cAMP by activating G protein-coupled adrenergic receptors; acting at cardiac β1-adrenergic receptors, agonists have positive inotropic, and lusitropic effects. ,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 435   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Catecholamine with Another pathway, Tyrosine with Another pathway, phenylalanine with Another pathway,

  ►  Pathway with its reference as follows :-
  • Catecholamine is derived from amino acid tyrosie & is synthesise from phenylalanine. --- ( WH, De John. "Elevated Urinary Free And Deconjugated Catecholamines After Consumption Of A Catecholamine-Rich Diet.". J clinic of Androcrine Metab 95.6 (2010): n. pag. Web. 23 Jan. 2017. )
  • Catecholamine is derived from amino acid tyrosie & is synthesise from phenylalanine. --- (WH, De John. "Elevated Urinary Free And Deconjugated Catecholamines After Consumption Of A Catecholamine-Rich Diet.". J clinic of Androcrine Metab 95.6 (2010): n. pag. Web. 23 Jan. 2017 )
  • Catecholamine is derived from amino acid tyrosie & is synthesise from phenylalanine. --- (WH, De John. "Elevated Urinary Free And Deconjugated Catecholamines After Consumption Of A Catecholamine-Rich Diet.". J clinic of Androcrine Metab 95.6 (2010): n. pag. Web. 23 Jan. 2017 )

  •   ►  URL -- https://www.ncbi.nlm.nih.gov/pubmed/20382681,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   2 minutes,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 1402   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA