Doxazosin is a Medicine belongs to Antihypertensive Agents group whose information about Brand can be referenced from   Book : Martindale    Page : 1403   Edition : 37,

  ►   Brandname : Doxacard,Cardura,Doxadura,Alfamedin,Cardular,Diblocin

  ►  Strength : Tablet with 1  mg, Tablet with 2  mg, Tablet with 4  mg, Tablet with 8  mg, Modified-release preparation with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 189   Edition : 12, Martindale    Page : 1403   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1403   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 hypertension Oral 1 mg Tablet h.s. Dose; Usual maintenance doses are up to 4 mg once daily; doses of 16 mg daily should not be exceeded
2 Benign prostatic hyperplasia Oral 1 mg Tablet h.s. Dose; usual maintenance dose is 2 to 4 mg daily; doses of 8 mg daily should not be exceeded.

Ref :-  Book : Martindale    Page : 1403   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 hypertension Oral 1 mg/day Tablet o.d.

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1645   Edition : 19,
►  Side Effect : Orthostatic hypotension, Dizziness, drowsiness, headache, lack of energy, nausea, palpitations, oedema, chest pain, dyspnoea, constipation, diarrhea, vomiting, Depression, Nervousness, Sleep disturbances, vertigo, hallucinations, paraesthesia, nasal congestion, epistaxis, dry mouth, urinary frequency, incontinence, reddened sclera, Blurred Vision, tinnitus, abnormal liver enzyme values, Pancreatitis, arthralgia, alopecia, lichen planus, Skin rashes, pruritus, diaphoresis, impotence, priapism,
Ref :-   Book : Martindale    Page : 1403,1510   Edition : 37,

►  Drug Interaction : Drug interaction of Doxazosin is with Diuretic Agents , , Alcohol, Beta Blockers , Calcium Channel Blockers ,  NA

  ►    Mechanism of Drug Drug Interaction :  The hypotensive effects of doxazosin may be enhanced by use with diuretics and other antihypertensives, and by alcohol and other drugs that cause hypotension. The risk of first-dose hypotension may be particularly increased in patients receiving beta blockers or calcium channel blockers,
Ref :-   Book : Martindale    Page : 1403,1510   Edition : 37,


►  Contraindication : hepatic impairment, renal impairment, heart failure, Doxazosin may cause drowsiness or dizziness; patients so affected should not drive or operate machinery,
Ref :-   Book : Martindale    Page : 1403,1510   Edition : 37,
  ►  Mechanism of Action :   Block endogenous catecholamines from binding to α1- and α2- adrenoceptors, causing vasodilation, decreased blood pressure, and decreased peripheral resistance ,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 145   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- beetroot with Another pathway,

  ►  Pathway with its reference as follows :-
  • Anti-hypertension effect . --- (PDR for Herbal medicines. (2000) (4th ed.). U.S. )

  •   ►  URL -- http://www.travolekar.ru/arch/Pdr_for_Herbal_Medicines.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Hepatic (Metabolism),
    Ref :-   Book : Martindale    Page : 1403   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   3 hours,
    Ref :-   Book : Martindale    Page : 1403   Edition : 37,