Dronabinol is a Medicine belongs to Antiemetic group whose information about Brand can be referenced from   Book : Martindale    Page : 1879   Edition : 37,

  ►   Brandname : Marinol

  ►  Strength : Capsule with 2.5  mg, Capsule with 5  mg, Capsule with 10  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 1111   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1879   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Nausea Oral 5 mg/m2 Capsule Dose: Given 1 to 3 hours before the first dose of the antineoplastic drug with subsequent doses being given every 2 to 4 hours after chemotherapy to a maximum of 4 to 6 doses daily
2 Vomiting Oral 5 mg/m2 Capsule Dose: Given 1 to 3 hours before the first dose of the antineoplastic drug with subsequent doses being given every 2 to 4 hours after chemotherapy to a maximum of 4 to 6 doses daily
3 Anorexia Oral 2.5 mg Capsule b.d. Dose: Given before lunch and supper reduced to a single 2.5-mg dose in the evening in patients who tolerate the drug poorly

Ref :-  Book : Martindale    Page : 1879   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Nausea Oral 2.5 5 mg/m2 Capsule

Ref :- Book : Nelson's textbook of Pediatrics    Page : 156   Edition : 19,
►  Side Effect : abdominal pain, nausea, vomiting, Dizziness, paranoid reactions, Somnolence, euphoria, mood changes, seizure-like activity,
Ref :-   Book : Martindale    Page : 1879   Edition : 37,

►  Drug Interaction : Drug interaction of Dronabinol is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : mania, Hypersensitivity,
Ref :-   Book : Martindale    Page : 1840   Edition : 37,
  ►  Mechanism of Action :   The exact mechanism of the anti-emetic action of dronabinol is not known but probably relates to stimulation of the CB1 subtype of cannabinoid receptors on neurons in and around the vomiting center in the brainstem.,
Ref :-   Book : Goodman    Page : 1345   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Ginger (Zingiber officinale) with Another pathway,

  ►  Pathway with its reference as follows :-
  • antiemetic effect . --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Biliary, Fecal, Hepatic (Metabolism), Renal,
    Ref :-   Book : Martindale    Page : 1879   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   4 hours,
    Ref :-   Book : Martindale    Page : 1879   Edition : 37,