Dutasteride is a Medicine belongs to Urological drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 2390   Edition : 37,

  ►   Brandname : Duprost,Avodart

  ►  Strength : Tablet with 0.5  mg,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 740   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 2390   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Benign prostatic hyperplasia Oral 500 micrograms Tablet Dose: given daily

Ref :-  Book : Martindale    Page : 2390   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : decreased libido, erectile dysfunction, reduced volume of ejaculate, hypersensitivity reactions, pruritus, Urticaria, Rashes, Testicular pain, breast tenderness, ejaculation disorders, swelling of the face, swelling of the lips, Breast enlargement (gynaecomastia),
Ref :-   Book : Martindale    Page : 2391,2391   Edition : 37,

►  Drug Interaction : Drug interaction of Dutasteride is with , , ,  NA

  ►    Mechanism of Drug Drug Interaction :  Dutasteride is metabolized by the cytochrome P450 isoenzymes CYP3A4 and CYP3A4. Dutasteride concentrations may be increased by moderate or potent inhibitors of CYP3A4 and a reduction of the Dutasteride concentrations may be increased by moderate or potent inhibitors of CYP3A4 and a reduction of the dutasteride dosing frequency may be considered if adverse effects are noted.,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : hepatic impairment, obstructive uropathy,
Ref :-   Book : Martindale    Page : 2390,2391   Edition : 37,
  ►  Mechanism of Action :   Dutasteride is an inhibitor of 5α-reductase. Unlike finasteride, it is claimed to inhibit both the type- 1 and type-2 isoforms of the enzyme.,
Ref :-   Book : Martindale    Page : 2390   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Lotus seed with Another pathway,

  ►  Pathway with its reference as follows :-
  • It is useful to treat benign prostatic hyperplasia (BPH) . --- (Stargrove, Michell Bebel. Hand Book Of Medicinal Herbs Second Edition. 2nd ed. United States of America: Linda Duncan, 2016. Print. )

  •   ►  URL -- https://books.google.co.in/books?id=B_XLBQAAQBAJ&printsec=frontcover&dq=hand+book+of+medicinal+herbs+second+edition&hl=en&sa=X&redir_esc=y#v=onepage&q=hand%20book%20of%20medicinal%20herbs%20second%20edition&f=false,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal,
    Ref :-   Book : Martindale    Page : 2390   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   3 weeks,    Max value :-   5 weeks,
    Ref :-   Book : Martindale    Page : 2390   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   3 hours,
    Ref :-   Book : Martindale    Page : 2390   Edition : 37,