Emtricitabine is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 964   Edition : 37,

  ►   Brandname : Emtriva

  ►  Strength : Tablet with 200  mg, Capsule with   , Oral solution with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 888   Edition : 12, Martindale    Page : 964   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 964   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 HIV infection and AIDS Oral 200 mg Capsule o.d.
2 HIV infection and AIDS Oral 240 mg Oral solution o.d.

Ref :-  Book : Martindale    Page : 964   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 HIV infection Oral 3 mg/kg Oral solution
2 HIV infection Oral 6 mg/kg Oral solution
3 HIV infection More then 30 kg Oral 200 mg Capsule

Ref :- Book : Martindale    Page : 964   Edition : 37,
►  Side Effect : headache, diarrhea, nausea, hyperpigmentation of the skin, abdominal pain, vomiting, dyspepsia, abnormal dreams, asthenia, Dizziness, insomnia, Pain, allergic skin reactions, pruritus, Rashes, Urticaria, Osteonecrosis, Immune reconstitution syndrome, hyperpigmented skin discoloration, neutropenia, anaemia, lipodystrophy, buffalo hump, peripheral wasting, facial wasting, breast enlargement, cushingoid appearance, hypertriglyceridaemia, hypercholesterolaemia, insulin resistance, Hyperglycaemia, Hyperlactataemia, abnormal behaviour, convulsion, hyperlipasaemia, hypertonia, Elevated creatine phosphokinase, myalgia, myositis, Ostenecrosis,
Ref :-   Book : Martindale    Page : 964   Edition : 37,

►  Drug Interaction : Drug interaction of Emtricitabine is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Emtricitabine should be given with caution to patients with hepatomegaly or other risk factors for liver disease, Patients co-infected with chronic hepatitis B or C and treated with combination antiretroviral therapy are at increased risk for severe and potentially fatal hepatic adverse events,
Ref :-   Book : Martindale    Page : 964   Edition : 37,
  ►  Mechanism of Action :   Emtricitabine is a nucleoside reverse transcriptase inhibitor related to cytosine with antiviral activity against HIV-1 and hepatitis B virus.Emtricitabine is converted intracellularly in stages to the triphosphate. This triphosphate halts the DNA synthesis of HIV through competitive inhibition of reverse transcriptase,
Ref :-   Book : Martindale    Page : 964   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Turmeric with Another pathway, Green tea with Another pathway,

  ►  Pathway with its reference as follows :-
  • Cucuritacins have Anti HIV activity --- (Aggarwal, B. & Harikumar, K. (2009). Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. The International Journal Of Biochemistry & Cell Biology, 41(1), 40-59. )
  • caffeic acid derivatives have Anti HIV activity. --- (Tran, J. (2013). Green Tea: A Potential Alternative Anti-Infectious Agent Catechins and Viral Infections. AA, 03(04), 198-202. http://dx.doi.org/10.4236/aa.2013.34028 )

  •   ►  URL -- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637808/, http://file.scirp.org/pdf/AA_2013110514091733.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 964   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   10 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 964   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   2 hours,
    Ref :-   Book : Martindale    Page : 964   Edition : 37,