Enfuvirtide is a Medicine belongs to Antiviral group whose information about Brand can be referenced from   Book : Martindale    Page : 965   Edition : 37,

  ►   Brandname : Fuzeon

  ►  Strength : Injection with 90  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 888   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : SC,
Reference :-   Book : Martindale    Page : 965   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 HIV infection and AIDS SC 90 mg Injection b.d. It is used with other antiretrovirals for combination therapy of HIV infection and AIDS

Ref :-  Book : Martindale    Page : 965   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 HIV infection 6 Year 16 Year SC 2 mg/kg Injection b.d.

Ref :- Book : Martindale    Page : 964   Edition : 37,
►  Side Effect : local injection site reactions with resultant pain, erythema, induration, nodules and cysts, pruritus, and ecchymosis, nausea, diarrhoea, weight loss, peripheral neuropathy, anorexia, abdominal pain, constipation, Pancreatitis, myalgia, weakness, Loss of strength, lymphadenopathy, insomnia, Depression, Flu-like illness, sinusitis, conjunctivitis, pneumonia, hypersensitivity reactions, anxiety, Hyperglycaemia, hypertriglyceridaemia, eosinophilia, Immune reconstitution syndrome, Osteonecrosis,
Ref :-   Book : Martindale    Page : 965   Edition : 37,

►  Drug Interaction : Drug interaction of Enfuvirtide is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : Systemic Hypersenstivity reaction , Pneumonia, hepatic impairment, severe renal impairment,
Ref :-   Book : Martindale    Page : 965   Edition : 37,
  ►  Mechanism of Action :   It is an HIV fusion inhibitor that interferes with entry of HIV into cells by binding to the gp41 subunit of the viral envelope glycoprotein, thereby inhibiting fusion of viral and cellular membranes,
Ref :-   Book : Martindale    Page : 965   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Ginger (Zingiber officinale) with Another pathway,

  ►  Pathway with its reference as follows :-
  • Anti viral activity. --- ( Chang, J., Wang, K., Yeh, C., Shieh, D., & Chiang, L. (2013). Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines. Journal Of Ethnopharmacology, 145(1), 146-151 )

  •   ►  URL -- http://www.ncbi.nlm.nih.gov/pubmed/23123794,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   NA


    ►    Plasma Half-life :
      Min value :-   3.8 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 965   Edition : 37,

    ►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
    Ref :-   Book :    Page :    Edition : ,