Eptifibatide is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1411   Edition : 37,

  ►   Brandname : Integrilin

  ►  Strength : Injection with 0.75  mg/ml, Injection with 2  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 617   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : IV,
Reference :-   Book : Martindale    Page : 1410   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 unstable angina IV 180 micrograms/kg Injection Dose: followed by 2 micrograms/kg per minute by intravenous infusion, for up to 72 hours. If percutaneous coronary intervention is performed during eptifibatide therapy, the infusion should be continued for 18 to 24 hours after the procedure, to a maximum total duration of 96 hours of therapy.
2 Angioplasty IV 180 micrograms/kg Injection Dose: Given immediately before the procedure, followed by 2 micrograms/kg per minute by intravenous infusion, with a second 180 microgram/kg intravenous injection given 10 minutes after the first. The infusion should be continued until hospital discharge or for up to 18 to 24 hours; a minimum of 12 hours is recommended.

Ref :-  Book : Martindale    Page : 1410-1411   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : bleeding, hypotension, thrombocytopenia,
Ref :-   Book : Martindale    Page : 1410   Edition : 37,

►  Drug Interaction : Drug interaction of Eptifibatide is with NA

  ►    Mechanism of Drug Drug Interaction :  ,
Ref :-   Book :    Page :    Edition : ,


►  Contraindication : aneurysm, arteriovenous malformation, Intracerebral neoplasm, thrombocytopenia, Uncontrolled hypertension, history of stroke, those recently undergone major surgery, severe trauma, emergency surgery required, Severe hepatic impairment, increased risk of haemorrhage, active bleeding,
Ref :-   Book : Martindale    Page : 1313,1411   Edition : 37,
  ►  Mechanism of Action :   Eptifibatide is an antiplatelet drug that reversibly inhibits binding of fibrinogen, von Willebrand factor, and other adhesive molecules to the glycoprotein IIb/IIIa receptor of platelets.,
Ref :-   Book : Martindale    Page : 1410   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 1410   Edition : 37,


►    Plasma Half-life :
  Min value :-   2.5 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 1410   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,