Ergocalciferol is a Medicine belongs to Vitamin group whose information about Brand can be referenced from   Book : Basic & Clinical pharmacology    Page : 786   Edition : 12,

  ►   Brandname : Vitamin D2,Calciferol,Drisdol

  ►  Strength : Capsule with 50000  IU, drops with 8000  mg/ml, Tablet with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 786   Edition : 12, Martindale    Page : 2153   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IM,
Reference :-   Book : Martindale    Page : 2150-2151   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Prevention of simple deficiency states Oral 10 micrograms Dose: (400 units) given daily.
2 Hypocalcemia due to hypoparathyroidism Oral 5 mg Dose: (200 000 units) daily.

Ref :-  Book : Martindale    Page : 2150   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Nutritional vitamin D deficiency rickets 1 Month 6 Month Oral 75 micrograms
2 Nutritional vitamin D deficiency rickets 6 Month 12 Year Oral 150 micrograms
3 Nutritional vitamin D deficiency rickets 12 Year 18 Year Oral 250 micrograms
4 Nutritional vitamin D deficiency 1 Year 12 Year Oral 250 625 micrograms
5 Nutritional vitamin D deficiency 1 Year 12 Year IM 250 625 Microgram Injection
6 Nutritional vitamin D deficiency 12 Year 18 Year Oral 250 1000 Microgram
7 Nutritional vitamin D deficiency 12 Year 18 Year IM 250 1000 Microgram Injection

Ref :- Book : Martindale    Page : 2151   Edition : 37,
►  Side Effect : Hyperphosphataemia, hypercalcemia, hypercalciuria, ectopic calcification, renal and cardiovascular damage, anorexia, lassitude, nausea, vomiting, constipation, diarrhea, polyuria, nocturia, headache, sweating, Somnolence, vertigo, hypersensitivity reactions, Skin irritation, Contact dermatitis,
Ref :-   Book : Martindale    Page : 2147   Edition : 37,

►  Drug Interaction : Drug interaction of Ergocalciferol is with ,  Oxcarbazepine , Carbamazapine , Phenobarbital , Phenytoin , Primidone , Rifampicin , Isoniazid , Corticosteroids, Ketoconazole ,
Ref :-   Book : Martindale    Page : 2149   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  There is an increased risk of hypercalcaemia if vitamin D is given with thiazide diuretics, calcium, or phosphate. Plasma-calcium concentrations should be monitored in such situations. Some antiepileptics may increase vitamin D requirements (e.g. carbamazepine, phenobarbital, phenytoin, and primidone). Rifampicin and isoniazid may reduce the effectiveness of vitamin D. Corticosteroids may counteract the effect of vitamin D. Ketoconazole may inhibit the metabolism of paricalcitol and these drugs should be used with caution together; care should be taken when using paricalcitol with other potent inhibitors of the cytochrome P450 isoenzyme CYP3A4.,
Ref :-   Book : Martindale    Page : 2149   Edition : 37,


►  Contraindication : renal impairment,
Ref :-   Book : Martindale    Page : 2149   Edition : 37,
  ►  Mechanism of Action :   Regulate gene transcription via the vitamin D receptor. ,
Ref :-   Book : Basic & Clinical pharmacology    Page : 785   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Biliary, Fecal, Renal,
Ref :-   Book : Martindale    Page : 2149   Edition : 37,


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA