Ethionamide is a Medicine belongs to Antibacterials group whose information about Brand can be referenced from   Book : Martindale    Page : 300   Edition : 37,

  ►   Brandname : Ethide,Myobid,Trecator

  ►  Strength : Tablet with 250  mg, Suppository with   , Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 848   Edition : 12, Martindale    Page : 300   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, rectal, IV,
Reference :-   Book : Martindale    Page : 300   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Resistant tuberculosis Oral 15 20 mg/kg Tablet Dose: maximum 1 g daily. Similar doses were used for the treatment of leprosy.

Ref :-  Book : Martindale    Page : 300   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 DRUG-RESISTANT TUBERCULOSIS Oral 15 20 mg/kg Tablet

Ref :- Book : Martindale    Page : 297   Edition : 37,
►  Side Effect : anorexia, nausea, vomiting, gastric irritation, Severe postural hypotension, mental depression, drowsiness, asthenia, olfactory disturbances, Blurred Vision, diplopia, Dizziness, paraesthesia, headache, Restlessness, tremor, severe skin rashes, purpura, stomatitis, Gynaecomastia, impotence, menorrhagia, acne, alopecia, metallic taste, hepatitis, ,
Ref :-   Book : Goodman    Page : 1562   Edition : 12,

►  Drug Interaction : Drug interaction of Ethionamide is with ,  Cycloserine ,
Ref :-   Book : Martindale    Page : 283,299   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  The adverse effects of other antimycobacterials may be increased when ethionamide is used. Neurotoxic effects may be potentiated by use of cycloserine with ethionamide,
Ref :-   Book : Martindale    Page : 283,299   Edition : 37,


►  Contraindication : Severe hepatic impairment,
Ref :-   Book : Martindale    Page : 299   Edition : 37,
  ►  Mechanism of Action :   Ethionamide, is chemically related to isoniazid and similarly block the synthesis of mycolic acid,
Ref :-   Book : Basic & Clinical pharmacology    Page : 843   Edition : 12,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism), Renal,
Ref :-   Book : Martindale    Page : 300   Edition : 37,


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA