Etizolam is a Medicine belongs to Anxiolytics Sedatives Hypnotics and Antipsychotics group whose information about Brand can be referenced from   Book : Martindale    Page : 1100   Edition : 37,    Page :   Edition : ,

  ►   Brandname : Depas; Pasaden,Ezolent

  ►  Strength : Tablet with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 1100   Edition : 37,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 1100   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Short term treatment of insomnia Oral up to 3 mg Dose: Given daily in divided doses or as a single dose at night.
2 Anxiety disorders Oral up to 3 mg Dose: Given daily in divided doses or as a single dose at night.

Ref :-  Book : Martindale    Page : 1100   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
►  Side Effect : drowsiness, Sedation, muscle weakness, ataxia, headache, vertigo, Confusion, Depression, slurred speech, dysesthesias, changes in libido, tremor, visual disturbances, urinary retention, incontinence, gastrointestinal disturbance, changes in salivation, amnesia, respiratory depression, hypotension, Pain, thrombophlebitis, hostility, aggression, disinhibition, ,
Ref :-   Book : Martindale    Page : 1090,1100   Edition : 37,

►  Drug Interaction : Drug interaction of Etizolam is with Alcohol, antidepressants, Antipsychotic , General anaesthetics , Hypnotics, Sedatives, opioid analgesics, Sedative antihistamines,  NA

  ►    Mechanism of Drug Drug Interaction :  Enhanced sedation or respiratory and cardiovascular depression may occur if diazepam or other benzodiazepines are given with other drugs that have CNS depressant properties; these include alcohol, antidepressants, sedative antihistamines, antipsychotics, general anaesthetics, other hypnotics or sedatives, and opioid analgesics. The metabolism of most banzodiazipines is mediated primarily by the cytochrome P450 system, particularly the isoenzymes CYP2C19 and CYP3A4. Hence, adverse effects may also be produce by use with drugs that inhibit or induce or metabolized by these isoenzymes. Benzodiazepines such as diazepam that are metabolised primarily by hepatic microsomal oxidation may be more susceptible to pharmacokinetic changes than those eliminated primarily by glucuronide conjugation. ,
Ref :-   Book : Martindale    Page : 1093,1100   Edition : 37,


►  Contraindication : hepatic impairment, Myasthenia gravis, pre-existing CNS depression or coma, respiratory depression, acute pulmonary insufficiency, renal impairment, sleep apnoea, chronic pulmonary insufficiency, Caution is required in patients with organic brain changes particularly arteriosclerosis,
Ref :-   Book : Martindale    Page : 1092,1100   Edition : 37,
  ►  Mechanism of Action :   Etizolam is a short-acting benzodiazepine derivative. Its actions are mediated by enhancement of the activity of gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain,
Ref :-   Book : Martindale    Page : 1100,1093   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Kava kava with Another pathway,

  ►  Pathway with its reference as follows :-
  • sedative effect . --- (Kokate, C. (2013). Pharmacognosy (4th ed.). Pune: Nirali Prakashan. )

  •   ►  URL -- http://freepharmadownloads.blogspot.com/2013/02/pharmacognosy-ckkokate-free-download.html,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Hepatic (Metabolism), Renal,
    Ref :-   Book : Martindale    Page : 1096,1100   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA