Exenatide is a Medicine belongs to Antidiabetic group whose information about Brand can be referenced from   Book : Basic & Clinical pharmacology    Page : 766   Edition : 12,

  ►   Brandname : Byetta

  ►  Strength : Injection with 250  mg/ml,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 766   Edition : 12,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : SC,
Reference :-   Book : Martindale    Page : 475   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Type 2 diabetes mellitus SC 5 micrograms Injection b.d. Dose: Given within 60 minutes before the morning and evening meals, which should be atleast 6 hours apart.

Ref :-  Book : Martindale    Page : 475   Edition : 37,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  

Ref :- Book :
Precaution :- If a Patient is using 'Exenatide' drug in chronic kidney disease disease, then Please give with caution in early stage and stop in stage 4/5 ckd   if he ever suffered from Diabetic Nephropathy disease.
►  Side Effect : vomiting, diarrhea, Nervousness, Dizziness, headache, dyspepsia, acute pancreatitis, asthenia, gastro-oesophageal reflux, Hyperhidrosis, Rashes, hypersensitivity reactions, decreased appetite, ,
Ref :-   Book : Martindale    Page : 474   Edition : 37,

►  Drug Interaction : Drug interaction of Exenatide is with ,  Warfarin , Metformin ,
Ref :-   Book : Martindale    Page : 475   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  A reduction in the sulfonylurea dose may be required when exenatide is added to therapy, because of an increased risk of hypoglycaemia with this combination. No increase in hypoglycaemia occurs when exenatide is used with metformin or a thiazolidinedione. The extent and rate of absorption of oral drugs may be reduced by exenatide. Where such an interaction would be undesirable, the oral medication should be given at least 1 hour before exenatide,
Ref :-   Book : Martindale    Page : 475   Edition : 37,


►  Contraindication : Type 1 diabetes mellitus, diabetic ketoacidosis, severe renal impairment,
Ref :-   Book : Martindale    Page : 475   Edition : 37,
  ►  Mechanism of Action :   Exenatide is a synthetic form of exendin-4, a 39-amino acid peptide isolated from the venom of the Gila monster lizard .The drug is an incretin mimic that acts as an agonist at the glucagon-like peptide 1 receptor to enhance insulin secretion in the presence of raised glucose concentrations; it also suppresses inappropriate glucagon secretion and slows gastric emptying,
Ref :-   Book : Martindale    Page : 475   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Renal,
Ref :-   Book : Martindale    Page : 475   Edition : 37,


►    Plasma Half-life :
  Min value :-   NA    Max value :-   NA


►    Peak Plasma Concentration :   Min value :-   2 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 475   Edition : 37,