Flecainide Acetate is a Medicine belongs to Cardiovascular drugs group whose information about Brand can be referenced from   Book : Martindale    Page : 1385   Edition : 38,

  ►   Brandname : Tambocor,Flecatab,Flecagamma

  ►  Strength : Tablet with 50  mg, Tablet with 100  mg, Tablet with 150  mg, Oral Suspension with   , Injection with   ,

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 249   Edition : 12, Martindale    Page : 1385   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral, IV,
Reference :-   Book : Martindale    Page : 1418   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Ventricular arrhythmias Oral 100 400 mg Tablet b.d.
2 Supraventricular arrhythmias Oral 50 300 mg Tablet b.d.
3 Arrhythmia IV 2 mg/kg Injection Given for rapid control of arrhythmias over 10 to 30 minutes, to a maximum dose of 150 mg; the ECG should be monitored. If longer term parenteral therapy is necessary it is started with i.v injection of 2 mg/kg, as above, then continued by i.v infusion of 1.5 mg/kg over the first hour, and 100 to 250 micrograms/kg per hour thereafter. The maximum cumulative dose in the first 24 hours should not exceed 600 mg. Infusion should not generally continue for more than 24 hours and oral therapy should be substituted as soon as possible.

Ref :-  Book : Martindale    Page : 1383   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Arrhythmia Oral 2 mg/kg Oral Suspension b.d/t.i.d
2 Arrhythmia 1 Month 12 Year Oral 2 8 mg/kg Oral Suspension b.d/t.i.d
3 Arrhythmia 1 Month 12 Year IV 2 mg/kg Injection
4 Arrhythmia

Ref :- Book : Martindale    Page : 1383   Edition : 38,
►  Side Effect : Dizziness, visual disturbances, lightheadedness, nausea, vomiting, headache, tremor, peripheral neuropathy, ataxia, paraesthesia, Corneal deposits, pulmonary fibrosis, and pneumonitis have occurred during long-term therapy, Ventricular tachyarrhythmias reported in patients with a history of ventricular tachyarrhythmias and taking high doses of flecainide, chest pain, myocardial infarction, , isolated cases of photosensitivity,
Ref :-   Book : Martindale    Page : 1418   Edition : 37,    Page :    Edition : ,

►  Drug Interaction : Drug interaction of Flecainide Acetate is with , , Beta Blockers ,  NA

  ►    Mechanism of Drug Drug Interaction :  Use of flecainide with other antiarrhythmics or arrhythmogenic drugs may increase the incidence of cardiac arrhythmias. Use with a beta blocker produces additive negative inotropic effects. Flecainide undergoes hepatic metabolism and its activity may be influenced by drugs that affect the enzymes responsible for its metabolism, including the cytochrome P450 isoenzyme CYP2D6.,
Ref :-   Book : Martindale    Page : 1418   Edition : 37,


►  Contraindication : cardiogenic shock, complete AV block,
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 419   Edition : 3,
  ►  Mechanism of Action :   Marked block of voltage-gated Na+ channels in ventricular myocytes (decreases phase 0 Upstroke velocity),
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 419   Edition : 3,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA


Dietry Substance Interactions


​   ► This Medicine interact with :- NA



ContraIndication Dietry Substance


​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Fecal, Renal, Hepatic (Metabolism),
Ref :-   Book : Martindale    Page : 1418   Edition : 37,


►    Plasma Half-life :
  Min value :-   20 hours,    Max value :-   NA
Ref :-   Book : Martindale    Page : 1418   Edition : 37,

►    Peak Plasma Concentration :   Min value :-   nf,    Max value :-   NA
Ref :-   Book :    Page :    Edition : ,