Fluoxymesterone is a Medicine belongs to Androgenic and anabolic steroids group whose information about Brand can be referenced from   Book : Martindale    Page : 2310   Edition : 37  

  ►   Brandname : Androxy
  ►  Strength : Tablet with 10 mg. 

Reference of this Medicine for its Strength can be taken from   Book : Basic & Clinical pharmacology    Page : 740   Edition : 12  
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral
Reference :-   Book : Martindale    Page : 2278   Edition : 38  

Dosing of Medicine differ in Adult & Pediatrics ↓

Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Inoperable neoplasms of the breast Oral 10 40 mg Tablet Given in the palliation of inoperable neoplasms in postmenopausal women. It is given daily in divided doses.
2 Male hypogonadism Oral 5 20 mg Given daily.

Ref :-  Book : Martindale    Page : 2278   Edition : 38  

Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Delayed puberty Oral 2.5 10 mg

Ref :- Book : Martindale    Page : 2278   Edition : 38  
►  Side Effect : Headache, Acne, Gynaecomastia, Oral irritation with buccal delivery, Skin irritation with transdermal delivery, Potential transfer to female partner with topical gel formulation, Cholestatic jaundice syndrome, Liver carcinoma, Benign prostatic hyperplasia , Prostate cancer
Ref :-   Book : Principle of Pharmacology (The Pathophysiologic Basis of Drug Therapy)    Page : 523   Edition : 3.  

►  Drug Interaction : Drug interaction of Fluoxymesterone is with Anticoagulant ,  Warfarin , Levothyroxine, Cyclosporine
Ref :-   Book : Martindale    Page : 2278,2308   Edition : 38.  

  ►    Mechanism of Drug Drug Interaction :  Testosterone and other androgens and anabolic steroids have been reported to enhance the activity of various drugs, with resulting increases in toxicity. Drugs affected include ciclosporin, levothyroxine, and anticoagulants such as warfarin. Resistance to the effects of neuromuscular blockers has also been reported. As androgens and anabolic steroids can alter glucose metabolism, doses of insulin or oral antidiabetics may need adjustment.
Ref :-   Book : Martindale    Page : 2278,2308   Edition : 38.  

►  Contraindication : Pregnant women or women who may become pregnant during the course of therapy, Male patients with carcinoma of the prostate or breast, Infants and young children
Ref :-   Book : Basic & Clinical pharmacology    Page : 737   Edition : 12.  
  ►  Mechanism of Action :   Testosterone derivatives alkylated at the 17 position, eg, methyltestosterone and Fluoxymesterone, are active when given by mouth. Like other steroids, testosterone acts intracellularly in target cells. In skin, prostate, seminal vesicles, and epididymis, it is converted to 5α-dihydrotestosterone by 5α-reductase. In these tissues, dihydrotestosterone is the dominant androgen. The distribution of this enzyme in the fetus is different and has important developmental implications. Testosterone and dihydrotestosterone bind to the intracellular androgen receptor, initiating a series of events similar to those described above for estradiol and progesterone, leading to growth, differentiation, and synthesis of a variety of enzymes and other functional proteins.
Ref :-   Book : Basic & Clinical pharmacology    Page : 735   Edition : 12.  

Pathway of DIETARY Product

​   ► Act.Comp / Nutrient / Food / Herb as follows :- NA

DIETARY Substance Interactions

​   ► This Medicine interact with :- NA

ContraIndication DIETARY Substance

​   ► This Medicine contraindicate with :- NA

►   Route of Elimination :   Hepatic (Metabolism)
Ref :-   Book : Martindale    Page : 2278,2308   Edition : 38.  

►    Plasma Half-life :   Min value :-   NA    Max value :-   NA

►    Peak Plasma Concentration :   Min value :-   NA    Max value :-   NA