Flutamide is a Medicine belongs to Antineoplastic group whose information about Brand can be referenced from   Book : Martindale    Page : 799   Edition : 38,

  ►   Brandname : Cytomid,Prostamid,Fluta,Chimax,Fugerel,Eulexin

  ►  Strength : Capsules with   ,

Reference of this Medicine for its Strength can be taken from   Book : Martindale    Page : 799   Edition : 38,
A Route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration.

  ►  Route of administration : Oral,
Reference :-   Book : Martindale    Page : 794   Edition : 37,

Dosing of Medicine differ in Adult & Pediatrics ↓


Adult Dose

S.No Ailment   Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency   Additional Info
1 Palliative treatment of prostatic carcinoma Oral 250 mg Capsules t.i.d. Used usually with gonadorelin analogues.

Ref :-  Book : Martindale    Page : 798   Edition : 38,




Pediatric Dose

S.No Ailment   Age Min   Age Max   Weight ( Kg ) Route   Dose Min   Dose Max   Unit   Dosage Form   Frequency  Additional Info  
1 Familial Male Gonadotropin-Independent Precocious Puberty 125 250 mg b.d.

Ref :- Book : Nelson's textbook of Pediatrics    Page : 1893   Edition : 19,
►  Side Effect : hot flashes, reversible gynaecomastia, breast tenderness, sometimes galactorrhoea, nausea, vomiting, diarrhea, increased appetite, anorexia, Sleep disturbances, There have been reports of skin reactions, including epidermal necrolysis, and of liver damage, sometimes fatal, anaemias, haemolysis, headache, Dizziness, malaise, Blurred Vision, anxiety, Depression, decreased libido, impotence, hypertension, Discoloration of the urine to amber or yellow-green, ,
Ref :-   Book : Martindale    Page : 794   Edition : 37,    Page :    Edition : ,

►  Drug Interaction : Drug interaction of Flutamide is with Warfarin ,
Ref :-   Book : Martindale    Page : 794   Edition : 37,


  ►    Mechanism of Drug Drug Interaction :  Flutamide may increase the effect of warfarin.,
Ref :-   Book : Martindale    Page : 794   Edition : 37,


►  Contraindication : Severe hepatic impairment,
Ref :-   Book : Martindale    Page : 799   Edition : 38,
  ►  Mechanism of Action :   Flutamide is a nonsteroidal compound with anti-androgenic properties which appears to act by inhibiting uptake and/or binding of androgens in target tissues.,
Ref :-   Book : Martindale    Page : 794   Edition : 37,

Pathway of Dietry Product


​   ► Act.Comp / Nutrient / Food / Herb as follows :- Angeer with Another pathway,

  ►  Pathway with its reference as follows :-
  • 6-o-acyl-beta-d-glucosyl-beta-sitosterols.found in fig or anjeer have anticancer property. --- (Joseph, Baby. "Pharmacognostic And Phytochemical Properties Of Ficus Carica Linn –An Overview". International Journal of PharmTech Research 3.1 (2017): 08-12,. Print. )

  •   ►  URL -- http://sphinxsai.com/Vol.3No.1/pharm_jan-mar11/pdf/JM11(%20PT=03)%2008-12.pdf,


    Dietry Substance Interactions


    ​   ► This Medicine interact with :- NA



    ContraIndication Dietry Substance


    ​   ► This Medicine contraindicate with :- NA

    ►   Route of Elimination :   Fecal, Renal,
    Ref :-   Book : Martindale    Page : 794   Edition : 37,


    ►    Plasma Half-life :
      Min value :-   NA    Max value :-   NA


    ►    Peak Plasma Concentration :   Min value :-   1 hours,    Max value :-   NA
    Ref :-   Book : Martindale    Page : 799   Edition : 38,